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Cheap flights from Panama City to Madrid, Spain from £429

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/3. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAD
26 Jan — 2 Feb1
1 adult

The best prices from Panama City Tocumen Intl to Madrid Barajas are usually found in February or March, booked 39 days in advance, depart on a Monday or Saturday and return on a Thursday

Cheap flight deals from Panama City to Madrid

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Madrid (MAD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 21 January 2025.

Round-trip from

£519

One-way from

£429

Popular in

July

Cheapest in

February

Average price

£649

Good one-way deal

£622 or less
Air Europa
  • Air Europa
  • 18/5-3/6
  • Nonstop
  • 20h 25m total
  • Panama City to Madrid
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Avianca
  • Avianca
  • 1/3
  • 2 total stops
  • 27h 05m total
  • Panama City to Madrid
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Highest demand for flights based on searches. 9% potential increase in price (£51 potential increase over avg. return price).
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Cheapest flight prices on average. 1% potential price decrease (£8 potential savings vs. average return price).
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Average for round-trip flights in January 2025
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Price to beat on a one-way flight from Panama City Tocumen Intl to Madrid Barajas.
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Find flight deals from Panama City to Madrid

Cheapest flights from Panama City to Madrid
Explore the most affordable flight options available from Panama City to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 21 January 2025.

Sun 18/520:25PTY - MAD
Nonstop9h 50mAir Europa
Tue 3/615:05MAD - PTY
Nonstop10h 35mAir Europa
Deal found 20/1£519
Sat 1/220:50PTY - MAD
1 stop14h 10mMultiple Airlines
Sat 15/317:00MAD - PTY
1 stop29h 25mMultiple Airlines
Deal found 20/1£574
Wed 5/218:45PTY - MAD
1 stop22h 40mKLM
Mon 5/506:00MAD - PTY
1 stop17h 50mKLM
Deal found 20/1£576
Mon 28/422:55PTY - MAD
2 stops25h 55mUnited Airlines
Tue 13/512:15MAD - PTY
2 stops22h 50mUnited Airlines
Deal found 21/1£586
Thu 6/218:20PTY - MAD
Nonstop10h 05mIberia
Sun 16/211:45MAD - PTY
Nonstop11h 05mIberia
Deal found 21/1£625
Sat 15/320:50PTY - MAD
1 stop16h 25mAir France
Mon 31/306:00MAD - PTY
2 stops17h 50mAir France
Deal found 20/1£632
Mon 3/203:19PTY - MAD
1 stop13h 16mAvianca
Tue 11/216:20MAD - PTY
1 stop14h 00mAvianca
Deal found 20/1£638
Tue 4/219:50PTY - MAD
1 stop38h 30mTurkish Airlines
Tue 18/214:55MAD - PTY
2 stops33h 25mTurkish Airlines
Deal found 21/1£668

Find flights from Panama City to Madrid within your budget

Customise your flight search to find flights from Panama City to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 January 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sun 18/5

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Tue 3/6

15:05-18:40

Nonstop10h 35m

£519

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sat 1/2

20:50-17:00

1 stop14h 10m

Madrid Barajas

Sat 15/3

17:00-16:25

1 stop29h 25m

£574

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Wed 5/2

18:45-23:25

1 stop22h 40m

Madrid Barajas

Mon 5/5

06:00-16:50

1 stop17h 50m

£576

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 28/4

22:55-07:50

2 stops25h 55m

Madrid Barajas

Fri 9/5

10:50-19:31

1 stop15h 41m

£586

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Thu 6/2

18:20-10:25

Nonstop10h 05m

Madrid Barajas

Sun 16/2

11:45-16:50

Nonstop11h 05m

£625

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sat 15/3

20:50-19:15

1 stop16h 25m

Madrid Barajas

Mon 31/3

06:00-16:50

2 stops17h 50m

£632

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 3/2

03:19-22:35

1 stop13h 16m

Madrid Barajas

Tue 11/2

16:20-00:20

1 stop14h 00m

£638

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Tue 4/2

19:50-16:20

1 stop38h 30m

Madrid Barajas

Tue 18/2

14:55-18:20

2 stops33h 25m

£668

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sat 1/3

13:30-22:35

2 stops27h 05m

£429

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Fri 14/2

21:45-10:25

1 stop30h 40m

£448

Flights are sorted by cheapest return flights first.

Deals found on 20/1

Showing 1-10 of 14 results
1
2

Best time to book a flight from Panama City to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City to Madrid

Get recent, data-driven insights about flights from Panama City to Madrid including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Panama City to Madrid?

Use this chart to determine the optimal time to book a return flight from Panama City to Madrid. Price data was last updated on 17 January 2025.

To ensure you get the cheapest price possible for a flight from Panama City to Madrid, you should look to book at least 39 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Panama City to Madrid?

Currently, January is the cheapest month in which you can book a flight from Panama City to Madrid (average of £94). Flying from Panama City to Madrid in August is currently the most expensive (average of £267). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to MAD?

Find hourly flight availability from Panama City to Madrid. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 21 January 2025.

It’s optimal to fly from Panama City to Madrid in the morning. By choosing this option you can save up to 26% on the cost of your flight, compared to a flight at midday.

Rainfall in Madrid by month

Plan your trip to Madrid by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Madrid ranges from 10.0 - 60.0 inches per month. November is typically the wettest month, when rainfall can reach 60.0 mm. July is typically the driest time to visit Madrid when rainfall is around 10.0 mm.

Temperature in Madrid by month

Plan your trip to Madrid by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Madrid, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 25.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 5.0 C).

Reviews of airlines servicing Madrid

Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated 21 January 2025.
See what other customers who have flown with Air France, Avianca and Air Europa from Panama City to Madrid have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,341 reviews
Check prices

Overall

7.8

Boarding

7.8

Crew

8.4

Comfort

7.7

Food

7.3

Entertainment

7.2

Reviews

1 / 10

I could not select a seat prior to check in as systems not integrated. Different PNRs should be on reservation which would make process easier.

KLM
7.8
Good
1,341 reviews
KLM
7.8
Good
1,341 reviews
Check prices

Overall

7.8

Boarding

7.8

Crew

8.4

Comfort

7.7

Food

7.3

Entertainment

7.2

Reviews

1 / 10

I could not select a seat prior to check in as systems not integrated. Different PNRs should be on reservation which would make process easier.

Air France
7.4
Good
1,490 reviews
KLM
7.8
Good
1,341 reviews
Check prices

Overall

7.8

Boarding

7.8

Crew

8.4

Comfort

7.7

Food

7.3

Entertainment

7.2

Reviews

1 / 10

I could not select a seat prior to check in as systems not integrated. Different PNRs should be on reservation which would make process easier.

United Airlines
7.4
Good
8,984 reviews
KLM
7.8
Good
1,341 reviews
Check prices

Overall

7.8

Boarding

7.8

Crew

8.4

Comfort

7.7

Food

7.3

Entertainment

7.2

Reviews

1 / 10

I could not select a seat prior to check in as systems not integrated. Different PNRs should be on reservation which would make process easier.

Turkish Airlines
7.3
Good
3,931 reviews
KLM
7.8
Good
1,341 reviews
Check prices

Overall

7.8

Boarding

7.8

Crew

8.4

Comfort

7.7

Food

7.3

Entertainment

7.2

Reviews

1 / 10

I could not select a seat prior to check in as systems not integrated. Different PNRs should be on reservation which would make process easier.

Iberia
7.0
Good
2,646 reviews
KLM
7.8
Good
1,341 reviews
Check prices

Overall

7.8

Boarding

7.8

Crew

8.4

Comfort

7.7

Food

7.3

Entertainment

7.2

Reviews

1 / 10

I could not select a seat prior to check in as systems not integrated. Different PNRs should be on reservation which would make process easier.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Panama City to Madrid?

    If you book a flight from Panama City to Madrid, you will be flying from Tocumen Intl to Barajas. Flights to Madrid Barajas (MAD) from Panama City Tocumen Intl (PTY) take 9h 35m for a nonstop flight. There are 3 flights from Tocumen Intl to Madrid per day from 2 airlines.

  • How popular is this Panama City to Madrid flight route?

    Flights from Panama City Tocumen Intl to Madrid Barajas have been viewed 21 times in the past calendar month.

  • What are the cheapest airlines flying from Panama City to Madrid round-trip?

    According to our current data, Air Europa (£519), KLM (£576), and United Airlines (£586) offers the cheapest pricing from Panama City to Madrid. Air Europa is 16% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Panama City to Madrid one-way?

    £429 is the cheapest one-way deal found within the past few days, from Avianca. You may also be able to find cheap deals on Turkish Airlines and United Airlines, with prices starting from £448 and £535, respectively.

  • What are the most reliable airlines from Panama City to Madrid?

    The top 3 most reliable airlines when flying from Panama City to Madrid are Air Europa (81%), Etihad Airways (77%) and Copa Airlines (63%).

  • What are the cheapest flights from Panama City to Madrid?

    Looking at all options, your cheapest flight can be booked for £502. While the most popular route (Panama City Tocumen Intl - Madrid Barajas) can be booked for £545 on average our data indicates £1,113 when flying from Panama City to Madrid.

  • Can I find deals for flights from Panama City to Madrid that include hotel bookings?

    Yes. In addition to deals on Panama City to Madrid flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Madrid.

  • Can I find deals for business class flights from Panama City to Madrid?

    Yes. Cheapflights offers flight deals from Panama City to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Madrid?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Madrid (average of £94). Flying from Panama City to Madrid in August is currently the most expensive (average of £267). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Guadalajara
Getafe

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Top 2 airlines flying from Panama City to Madrid

Discover the top 2 airlines that operate flights from Panama City to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 January 2025.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapest£511Average£631FlexibilityNo cancel feeOn-time83%
Search Air Europa flights
IberiaCheapest£540Average£696FlexibilityNo cancel feeOn-time77%
Search Iberia flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama City to Madrid?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Panama City to Madrid. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Panama City to Madrid?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City to Madrid for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Panama City to Madrid with no change fees?

Certainly. Search results for flights to Madrid from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama City to Madrid become cheaper?

Of course! You can now track prices for flights from Panama City to Madrid and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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