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Cheap flights from Missouri to Manchester from £305

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 17/5. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAN
29 Apr — 6 May1
1 adult

Cheap flight deals from Missouri to Manchester

Keep the following information in mind while searching for Missouri to Manchester flight deals. Data was last updated 24 April 2025.

Round-trip from

£524

One-way from

£305

Popular in

June

Cheapest in

February

Average price

£708
United Airlines
  • United Airlines
  • 6/5-9/5
  • 4 total stops
  • 68h 49m total
  • Missouri to Manchester
17/5
  • 17/5
  • 3 total stops
  • 58h 53m total
  • Missouri to Manchester
Highest demand for flights based on searches. 25% potential increase in price (£178 potential increase over avg. return price).
Cheapest flight prices on average. 6% potential price decrease (£30 potential savings vs. average return price).
Average for round-trip flights in April 2025

Find flight deals from Missouri to Manchester

Cheapest flights from Missouri to Manchester
Explore the most affordable flight options available from Missouri to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 24 April 2025.

Tue 6/517:29STL - MAN
2 stops34h 56mUnited Airlines
Fri 9/506:05MAN - STL
2 stops33h 53mUnited Airlines
Deal found 22/4£524
Tue 6/512:51STL - MAN
1 stop13h 44mVirgin Atlantic
Fri 9/512:35MAN - STL
1 stop14h 04mVirgin Atlantic
Deal found 22/4£552
Sun 21/910:35MCI - MAN
1 stop16h 00mDelta
Fri 26/912:35MAN - MCI
1 stop15h 46mDelta
Deal found 23/4£552
Tue 6/512:51STL - MAN
1 stop13h 44mDelta
Fri 9/514:15MAN - STL
2 stops25h 20mDelta
Deal found 22/4£555
Wed 15/1014:04MCI - MAN
2 stops22h 46mFinnair
Tue 21/1017:50MAN - MCI
2 stops30h 20mFinnair
Deal found 23/4£555
Tue 23/918:29MCI - MAN
2 stops16h 56mUnited Airlines
Thu 25/906:05MAN - MCI
2 stops23h 22mUnited Airlines
Deal found 23/4£573
Wed 7/513:15MCI - MAN
1 stop13h 20mVirgin Atlantic
Fri 23/512:35MAN - MCI
1 stop13h 52mVirgin Atlantic
Deal found 24/4£606
Wed 26/1114:07MCI - MAN
2 stops17h 48mMultiple Airlines
Mon 1/1218:00MAN - MCI
2 stops30h 11mMultiple Airlines
Deal found 22/4£610
Wed 7/513:48MCI - MAN
2 stops17h 22mBritish Airways
Fri 23/508:40MAN - MCI
2 stops19h 10mBritish Airways
Deal found 24/4£622
Thu 25/913:30STL - MAN
2 stops38h 50mMultiple Airlines
Sat 4/1009:10MAN - STL
2 stops16h 23mMultiple Airlines
Deal found 23/4£636
Wed 15/1009:58MCI - MAN
3 stops18h 27mAir Canada
Tue 21/1006:05MAN - MCI
3 stops17h 25mAir Canada
Deal found 23/4£651
Thu 25/912:28STL - MAN
2 stops16h 12mLufthansa
Sat 4/1018:10MAN - STL
1 stop25h 20mLufthansa
Deal found 23/4£673

Cheapflights Fare Finder

Customise your flight search to find flights from Missouri to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 24 April 2025.
Use the filters below to find and compare flights from Missouri to Manchester that are best for you.

Fly from

Missouri

Fly to

Manchester

Route

Depart

Return

Price

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 6/5

17:29-10:25

2 stops34h 56m

Manchester

Fri 9/5

06:05-09:58

2 stops33h 53m

£524

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 6/5

12:51-08:35

1 stop13h 44m

Manchester

Fri 9/5

12:35-20:39

1 stop14h 04m

£552

Kansas CityManchester

MCI - MAN

MCIMAN

Kansas City

Sun 21/9

10:35-08:35

1 stop16h 00m

Manchester

Fri 26/9

12:35-22:21

1 stop15h 46m

£552

Kansas CityManchester

MCI - MAN

MCIMAN

Kansas City

Wed 15/10

14:04-18:50

2 stops22h 46m

Manchester

Tue 21/10

17:50-18:10

2 stops30h 20m

£555

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Tue 6/5

12:51-08:35

1 stop13h 44m

Manchester

Fri 9/5

14:15-09:35

2 stops25h 20m

£555

Kansas CityManchester

MCI - MAN

MCIMAN

Kansas City

Tue 23/9

18:29-17:25

2 stops16h 56m

Manchester

Thu 25/9

06:05-23:27

2 stops23h 22m

£573

Kansas CityManchester

MCI - MAN

MCIMAN

Kansas City

Wed 7/5

13:15-08:35

1 stop13h 20m

Manchester

Fri 23/5

12:35-20:27

1 stop13h 52m

£606

Kansas CityManchester

MCI - MAN

MCIMAN

Kansas City

Wed 7/5

13:48-13:10

2 stops17h 22m

Manchester

Fri 23/5

08:40-21:50

2 stops19h 10m

£622

St. LouisManchester

STL - MAN

STLMAN

Lambert-St Louis

Thu 25/9

13:30-10:20

2 stops38h 50m

Manchester

Sat 4/10

09:10-19:33

2 stops16h 23m

£636

Kansas CityManchester

MCI - MAN

MCIMAN

Kansas City

Wed 15/10

09:58-10:25

3 stops18h 27m

Manchester

Tue 21/10

06:05-17:30

3 stops17h 25m

£651

Flights are sorted by cheapest return flights first.

Deals found on 22/4

Showing 1-10 of 22 results
1
2
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Best time to book a flight from Missouri to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Missouri with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Manchester

What is the cheapest month to book a flight from Missouri to Manchester?

Currently, January is the cheapest month in which you can book a flight from Missouri to Manchester (average of £117). Flying from Missouri to Manchester in September is currently the most expensive (average of £143). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MAN?

Find hourly flight availability from Missouri to Manchester. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 24 April 2025.

When flying from Missouri to Manchester, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Manchester by month

Plan your trip to Manchester by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Manchester ranges from 50.0 - 90.0 inches per month. August is typically the wettest month, when rainfall can reach 90.0 mm. February is typically the driest time to visit Manchester when rainfall is around 50.0 mm.

Temperature in Manchester by month

Plan your trip to Manchester by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Manchester, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 17.0 C. Travellers hoping to avoid the cold should look outside of December, when temperatures are typically at their lowest (around 4.0 C).

Reviews of airlines servicing Manchester

Get insights into the airlines that provide service to Manchester. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Manchester. Reviews last updated 24 April 2025.
Get a feel of what it's like to fly with Delta, Finnair and United Airlines from Missouri to Manchester by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very Good

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Manchester from Missouri?

    For a flight from Missouri to Manchester, you will be flying into Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.

  • What are the most popular routes from Missouri to Manchester?

  • Can I find deals for flights from Missouri to Manchester that include hotel bookings?

    Yes. In addition to deals on Missouri to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Manchester.

  • Can I find deals for business class flights from Missouri to Manchester?

    Yes. Cheapflights offers flight deals from Missouri to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Manchester?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Manchester (average of £117). Flying from Missouri to Manchester in September is currently the most expensive (average of £143). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Missouri?

Book flights to Missouri if you plan to visit one of these locations
Llandudno
Bradford
Derby
Windermere
Harrogate
Preston
Morecambe
Stoke-on-Trent
Blackburn
Salford
Bolton
Lincoln
Stockport
Southport
Chesterfield
Wakefield
Sale
Huddersfield
Telford
Oswestry

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Manchester

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Missouri to Manchester

Discover the top airline that operate flights from Missouri to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 24 April 2025.
AirlineCheapestAverageFlexibilityOn-time
Virgin AtlanticCheapest£453Average£563FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights

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Users can book flights with no change fees policies with our dedicated filters. Book flights from Missouri to Manchester flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Missouri to Manchester become cheaper?

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