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Cheap flights from Panama City to Mexico City from £199

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 21/3. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MEX
26 Feb — 5 Mar1
1 adult

The best prices from Panama City Tocumen Intl to Mexico City Benito Juarez are usually found in February or January, booked 84 days in advance, depart on a Wednesday or Thursday and return on a Tuesday

Cheap flight deals from Panama City to Mexico City

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 21 February 2025.

Round-trip from

£362

One-way from

£199

Popular in

June

Cheapest in

February

Average price

£334

Good round-trip deal

£315 or less
Aeromexico
  • Aeromexico
  • 18/6-27/6
  • Nonstop
  • 7h 30m total
  • Panama City to Mexico City
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Avianca
  • Avianca
  • 21/3
  • 1 total stop
  • 15h 51m total
  • Panama City to Mexico City
Search Deals
Highest demand for flights based on searches. 6% potential increase in price (£19 potential increase over avg. return price).
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Cheapest flight prices on average. 1% potential price decrease (£4 potential savings vs. average return price).
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Average for round-trip flights in February 2025
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Price to beat on a round-trip flight from Panama City Tocumen Intl to Mexico City Benito Juarez.
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Find flight deals from Panama City to Mexico City

Cheapest flights from Panama City to Mexico City
Explore the most affordable flight options available from Panama City to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 21 February 2025.

Sun 14/903:20PTY - MEX
1 stop15h 45mAvianca
Mon 29/900:40MEX - PTY
1 stop7h 15mAvianca
Deal found 20/2£336
Wed 18/615:02PTY - MEX
Nonstop3h 38mAeromexico
Fri 27/608:55MEX - PTY
Nonstop3h 52mAeromexico
Deal found 20/2£362
Fri 11/419:08PTY - MEX
Nonstop3h 52mCopa Airlines
Sun 20/409:50MEX - PTY
Nonstop3h 43mCopa Airlines
Deal found 19/2£383
Fri 11/417:25PTY - MEX
1 stop10h 40mMultiple Airlines
Sun 20/409:55MEX - PTY
1 stop8h 34mMultiple Airlines
Deal found 19/2£564
Fri 11/413:15PTY - MEX
2 stops22h 05mAmerican Airlines
Sun 20/405:00MEX - PTY
2 stops30h 15mAmerican Airlines
Deal found 19/2£728
Thu 6/323:55PTY - MEX
2 stops25h 15mUnited Airlines
Tue 11/308:40MEX - PTY
2 stops18h 32mUnited Airlines
Deal found 20/2£1,123

Find flights from Panama City to Mexico City within your budget

Customise your flight search to find flights from Panama City to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 February 2025.

Fly from

Panama City

Fly to

Mexico City

Route

Depart

Return

Price

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Wed 18/6

15:02-17:40

Nonstop3h 38m

Mexico City Benito Juarez

Fri 27/6

08:55-13:47

Nonstop3h 52m

£362

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Fri 11/4

19:08-22:00

Nonstop3h 52m

Mexico City Benito Juarez

Sun 20/4

09:50-14:33

Nonstop3h 43m

£383

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Fri 11/4

17:25-03:05

1 stop10h 40m

Mexico City Benito Juarez

Sun 20/4

14:00-00:10

1 stop9h 10m

£551

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Fri 11/4

17:25-03:05

1 stop10h 40m

Mexico City Benito Juarez

Sun 20/4

09:55-19:29

1 stop8h 34m

£564

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Fri 11/4

13:15-10:20

2 stops22h 05m

Mexico City Benito Juarez

Sun 20/4

05:00-12:15

2 stops30h 15m

£728

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Thu 6/3

23:55-00:10

2 stops25h 15m

Mexico City Benito Juarez

Tue 11/3

08:40-04:12

2 stops18h 32m

£1,123

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Fri 21/3

03:19-18:10

1 stop15h 51m

£199

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Wed 26/2

09:11-12:10

Nonstop3h 59m

£399

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Wed 26/2

18:28-18:55

2 stops25h 27m

£763

Flights are sorted by cheapest return flights first.

Deals found on 20/2

Best time to book a flight from Panama City to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City to Mexico City

Get recent, data-driven insights about flights from Panama City to Mexico City including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Panama City to Mexico City?

Use this chart to determine the optimal time to book a return flight from Panama City to Mexico City. Price data was last updated on 14 February 2025.

The price you pay for your flight from Panama City to Mexico City may vary depending on when you book. For the best chance of a lower fare, look to book 62 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to Mexico City?

Currently, April is the cheapest month in which you can book a flight from Panama City to Mexico City (average of £791). Flying from Panama City to Mexico City in July is currently the most expensive (average of £1,261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to MEX?

Find hourly flight availability from Panama City to Mexico City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 21 February 2025.

It’s optimal to fly from Panama City to Mexico City at midday. By choosing this option you can save up to 20% on the cost of your flight, compared to a flight in the morning.

Weekly flight availability from Panama City to Mexico City

Explore weekly flight availability from Panama City to Mexico City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 21 February 2025.

The most flights from PTY to MEX are scheduled on a Wednesday (10 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (5 on average).

Rainfall in Mexico City by month

Plan your trip to Mexico City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mexico City ranges from 0.0 - 120.0 inches per month. July is typically the wettest month, when rainfall can reach 120.0 mm. January is typically the driest time to visit Mexico City when rainfall is around 0.0 mm.

Temperature in Mexico City by month

Plan your trip to Mexico City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mexico City, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 19.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 13.0 C).

Reviews of airlines servicing Mexico City

Get insights into the airlines that provide service to Mexico City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City. Reviews last updated 21 February 2025.
To help decide which airline to fly from Panama City to Mexico City, see what other customers have to say about Copa Airlines, Aeromexico and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,510 reviews
Check prices

Crew

8.1

Boarding

7.8

Entertainment

6.9

Comfort

7.4

Overall

7.6

Food

6.9

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Copa Airlines
7.6
Good
1,510 reviews
Copa Airlines
7.6
Good
1,510 reviews
Check prices

Crew

8.1

Boarding

7.8

Entertainment

6.9

Comfort

7.4

Overall

7.6

Food

6.9

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Aeromexico
7.5
Good
1,771 reviews
Copa Airlines
7.6
Good
1,510 reviews
Check prices

Crew

8.1

Boarding

7.8

Entertainment

6.9

Comfort

7.4

Overall

7.6

Food

6.9

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

United Airlines
7.4
Good
8,760 reviews
Copa Airlines
7.6
Good
1,510 reviews
Check prices

Crew

8.1

Boarding

7.8

Entertainment

6.9

Comfort

7.4

Overall

7.6

Food

6.9

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

American Airlines
7.2
Good
10,000 reviews
Copa Airlines
7.6
Good
1,510 reviews
Check prices

Crew

8.1

Boarding

7.8

Entertainment

6.9

Comfort

7.4

Overall

7.6

Food

6.9

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Avianca
6.8
Okay
2,431 reviews
Copa Airlines
7.6
Good
1,510 reviews
Check prices

Crew

8.1

Boarding

7.8

Entertainment

6.9

Comfort

7.4

Overall

7.6

Food

6.9

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Panama City to Mexico City?

    You will need to book a flight from Panama City Tocumen Intl to Mexico City Benito Juarez if you want to fly from Panama City to Mexico City. At least 1 airline has flights from Tocumen Intl (PTY) to Benito Juarez (MEX) on a regular basis. There are 7 flights to Mexico City from the Panama City airport per day. If you manage to book one that is nonstop, then you can expect the flight time from PTY to MEX to be around 3h 52m.

  • How popular is this Panama City to Mexico City flight route?

    The Panama City Tocumen Intl to Mexico City Benito Juarez flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Panama City to Mexico City round-trip?

    Flying on Aeromexico is currently your cheapest option to Mexico City, with prices starting at £362. Additional return tickets that might be worth considering are offered by Copa Airlines and Avianca, with the lowest prices starting at £383 and £551, respectively. You may be able to fly from Panama City to Mexico City for 3% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Panama City to Mexico City one-way?

    To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at £199. Copa Airlines flights start at £399 while deals on United Airlines start at £763 one-way.

  • What are the cheapest flights from Panama City to Mexico City?

    On average you can expect to pay £318 for a flight from Panama City to Mexico City. The cheapest flight overall is £307 while the most popular route, (Panama City Tocumen Intl - Mexico City Benito Juarez) is currently priced at £326.

  • Can I find deals for flights from Panama City to Mexico City that include hotel bookings?

    Yes. In addition to deals on Panama City to Mexico City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Mexico City.

  • Can I find deals for business class flights from Panama City to Mexico City?

    Yes. Cheapflights offers flight deals from Panama City to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Mexico City?

    Currently, April is the cheapest month in which you can book a flight from Panama City to Mexico City (average of £791). Flying from Panama City to Mexico City in July is currently the most expensive (average of £1,261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Panama City to Mexico City

Discover the top airline that operate flights from Panama City to Mexico City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 February 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest£295Average£348FlexibilityNo cancel feeOn-time70%
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Can Cheapflights notify me if prices for flights from Panama City to Mexico City become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Mexico City from Panama City today and book when prices fit your budget.

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