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Cheap flights from Panama City to Brussels Bruxelles-National Airport from £448

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 26/4. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — BRU
5 Apr — 12 Apr1
1 adult

Cheap flight deals from Panama City to Bruxelles-National

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Bruxelles-National (BRU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 31 March 2025.

Round-trip from

£610

One-way from

£448

Popular in

July

Cheapest in

October

Average price

£644
Air Europa
  • Air Europa
  • 11/5-25/5
  • 2 total stops
  • 45h 00m total
  • Panama City to Brussels
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Turkish Airlines
  • Turkish Airlines
  • 26/4
  • 1 total stop
  • 38h 50m total
  • Panama City to Brussels
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Highest demand for flights based on searches. 10% potential increase in price (£56 potential increase over avg. return price).
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Cheapest flight prices on average. 1% potential price decrease (£7 potential savings vs. average return price).
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Average for round-trip flights in March 2025
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Find flight deals from Panama City to Bruxelles-National

Cheapest flights from Panama City to Bruxelles-National
Explore the most affordable flight options available from Panama City to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 31 March 2025.

Sun 11/520:25PTY - BRU
1 stop14h 15mAir Europa
Sun 25/518:55BRU - PTY
1 stop30h 45mAir Europa
Deal found 30/3£610
Mon 8/918:50PTY - BRU
1 stop12h 45mKLM
Fri 12/910:25BRU - PTY
1 stop13h 25mKLM
Deal found 31/3£712
Sun 11/521:55PTY - BRU
1 stop29h 15mTurkish Airlines
Sun 25/514:25BRU - PTY
2 stops34h 55mTurkish Airlines
Deal found 31/3£715
Tue 6/522:55PTY - BRU
2 stops27h 05mUnited Airlines
Tue 20/511:15BRU - PTY
1 stop15h 16mUnited Airlines
Deal found 31/3£814

Cheapflights Fare Finder

Customise your flight search to find flights from Panama City to Bruxelles-National that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 31 March 2025.
Use the filters below to find and compare flights from Panama City to Brussels Bruxelles-National Airport that are best for you.

Fly from

Panama City

Fly to

Bruxelles-National

Route

Depart

Return

Price

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 11/5

20:25-17:40

1 stop14h 15m

Brussels Bruxelles-National

Sun 25/5

18:55-18:40

1 stop30h 45m

£610

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 8/9

18:50-14:35

1 stop12h 45m

Brussels Bruxelles-National

Fri 12/9

10:25-16:50

1 stop13h 25m

£712

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 11/5

21:55-10:10

1 stop29h 15m

Brussels Bruxelles-National

Sun 25/5

14:25-18:20

2 stops34h 55m

£715

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Tue 6/5

22:55-09:00

2 stops27h 05m

Brussels Bruxelles-National

Tue 20/5

11:15-19:31

1 stop15h 16m

£814

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 26/4

20:00-17:50

1 stop38h 50m

£448

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 5/4

09:45-07:45

1 stop15h 00m

£732

Flights are sorted by cheapest return flights first.

Deals found on 31/3

Best time to book a flight from Panama City to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Brussels Bruxelles-National Airport

How far ahead should I book a flight from Panama City to Brussels Bruxelles-National Airport?

Use this chart to determine the optimal time to book a return flight from Panama City to Bruxelles-National. Price data was last updated on 28 March 2025.

To ensure you get the cheapest price possible for a flight from Panama City to Brussels Bruxelles-National Airport, you should look to book at least 28 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Panama City to Brussels Bruxelles-National Airport?

Currently, January is the cheapest month in which you can book a flight from Panama City to Brussels Bruxelles-National Airport (average of £117). Flying from Panama City to Brussels Bruxelles-National Airport in July is currently the most expensive (average of £172). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Bruxelles-National by month

Plan your trip to Bruxelles-National by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Brussels Bruxelles-National Airport ranges from 40.0 - 80.0 inches per month. January is typically the wettest month, when rainfall can reach 80.0 mm. August is typically the driest time to visit Brussels Bruxelles-National Airport when rainfall is around 40.0 mm.

Temperature in Bruxelles-National by month

Plan your trip to Bruxelles-National by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Brussels Bruxelles-National Airport, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 17.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 3.0 C).

Reviews of airlines servicing Bruxelles-National

Get insights into the airlines that provide service to Bruxelles-National. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Bruxelles-National. Reviews last updated 31 March 2025.
KLM
7.8
Good
1,321 reviews
Check prices

Overall

7.8

Crew

8.4

Entertainment

7.1

Food

7.3

Boarding

7.8

Comfort

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.
KLM
7.8
Good
1,321 reviews
KLM
7.8
Good
1,321 reviews
Check prices

Overall

7.8

Crew

8.4

Entertainment

7.1

Food

7.3

Boarding

7.8

Comfort

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.
United Airlines
7.4
Good
8,614 reviews
KLM
7.8
Good
1,321 reviews
Check prices

Overall

7.8

Crew

8.4

Entertainment

7.1

Food

7.3

Boarding

7.8

Comfort

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.
Turkish Airlines
7.3
Good
3,748 reviews
KLM
7.8
Good
1,321 reviews
Check prices

Overall

7.8

Crew

8.4

Entertainment

7.1

Food

7.3

Boarding

7.8

Comfort

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.
Air Europa
6.9
Okay
504 reviews
KLM
7.8
Good
1,321 reviews
Check prices

Overall

7.8

Crew

8.4

Entertainment

7.1

Food

7.3

Boarding

7.8

Comfort

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Bruxelles-National. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Brussels Bruxelles-National?

    Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly out of when you book flights from Panama City to Brussels Bruxelles-National. 0 airlines have flights from Tocumen Intl to Brussels Bruxelles-National on a regular basis. Booking flights from Panama City Tocumen Intl to Brussels Bruxelles-National should not be difficult; the airport handles an average of 0 outbound flights to Brussels Bruxelles-National per day.

  • What are the cheapest airlines flying from Panama City to Brussels Bruxelles-National Airport round-trip?

    Flying on Air Europa is currently your cheapest option to Brussels Bruxelles-National Airport, with prices starting at £610. Additional return tickets that might be worth considering are offered by KLM and Turkish Airlines, with the lowest prices starting at £712 and £715, respectively. You may be able to fly from Panama City to Brussels Bruxelles-National Airport for 6% less than the average price by searching for these airlines.

  • Can I find deals for flights from Panama City to Bruxelles-National that include hotel bookings?

    Yes. In addition to deals on Panama City to Bruxelles-National flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Bruxelles-National?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Bruxelles-National.

  • Can I find deals for business class flights from Panama City to Bruxelles-National?

    Yes. Cheapflights offers flight deals from Panama City to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Brussels Bruxelles-National Airport?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Brussels Bruxelles-National Airport (average of £117). Flying from Panama City to Brussels Bruxelles-National Airport in July is currently the most expensive (average of £172). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Deals for Panama City to Bruxelles-National flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Panama City to Bruxelles-National?

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Can Cheapflights find flights from Panama City to Bruxelles-National with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Panama City to Bruxelles-National flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Panama City to Bruxelles-National become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Bruxelles-National from Panama City today and book when prices fit your budget.

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