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Cheap flights from London Heathrow Airport to Panama City, Florida from £485

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19/6. Fares are subject to change and may not be available on all flights or dates of travel.
LHR — ECP
2 May — 9 May1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Heathrow to Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Heathrow to Panama City
Explore the most affordable flight options available from Heathrow to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 2 April 2026.

Mon 20/416:25
LHR
-
ECP
1 stop25h 10m
American Airlines
Tue 5/511:43
ECP
-
LHR
2 stops16h 32m
American Airlines
Deal found 30/3£533
Wed 29/409:30
LHR
-
ECP
2 stops18h 29m
United Airlines
Wed 6/511:29
ECP
-
LHR
1 stop14h 16m
United Airlines
Deal found 30/3£575
Mon 27/411:45
LHR
-
ECP
2 stops33h 41m
Virgin Atlantic
Tue 5/513:33
ECP
-
LHR
2 stops17h 02m
Virgin Atlantic
Deal found 30/3£576
Wed 29/411:15
LHR
-
ECP
1 stop17h 57m
Virgin Atlantic
Wed 6/517:10
ECP
-
LHR
1 stop14h 05m
Virgin Atlantic
Deal found 30/3£587
Mon 20/410:05
LHR
-
ECP
1 stop17h 53m
American Airlines
Wed 6/513:08
ECP
-
LHR
2 stops14h 42m
American Airlines
Deal found 30/3£598
Thu 3/1206:35
LHR
-
ECP
2 stops19h 31m
United Airlines
Mon 7/1210:25
ECP
-
LHR
2 stops18h 25m
United Airlines
Deal found 30/3£602
Sun 26/417:35
LHR
-
ECP
2 stops27h 51m
Delta
Sun 3/518:46
ECP
-
LHR
1 stop29h 39m
Delta
Deal found 28/3£615

Find flight deals from Heathrow to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Heathrow (LHR) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 2 April 2026.

Round-trip from

£533

One-way from

£485

Popular in

December

Cheapest in

September

Average price

£525
American Airlines
  • American Airlines
  • 20/4-5/5
  • 3 total stops
  • 41h 42m total
  • London to Panama City
Search Deals
United Airlines
  • United Airlines
  • 19/6
  • 1 total stop
  • 33h 51m total
  • London to Panama City
Search Deals
Highest demand for flights based on searches. 3% potential increase in price (£18 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease (£22 potential savings vs. average return price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Heathrow to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 2 April 2026.
Use the filters below to find and compare flights from London Heathrow Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Mon 8/6

10:00-13:51

1 stop33h 51m

Panama City NW Florida Beaches

Mon 15/6

06:30-08:20

2 stops19h 50m

£666

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Fri 15/5

13:40-22:05

1 stop14h 25m

Panama City NW Florida Beaches

Fri 22/5

10:25-07:15

2 stops14h 50m

£678
Fastest return journey

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Sun 26/4

09:20-15:26

1 stop12h 06m

Panama City NW Florida Beaches

Sun 3/5

09:21-06:25

1 stop15h 04m

£702

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Sun 12/4

10:00-21:59

1 stop17h 59m

Panama City NW Florida Beaches

Fri 8/5

06:30-11:35

1 stop23h 05m

£704

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Fri 1/5

17:05-10:03

2 stops22h 58m

Panama City NW Florida Beaches

Sun 31/5

15:48-10:50

1 stop13h 02m

£722

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Sat 16/5

13:40-22:05

1 stop14h 25m

Panama City NW Florida Beaches

Sat 23/5

06:30-07:55

1 stop19h 25m

£725

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Thu 4/6

13:40-13:51

1 stop30h 11m

Panama City NW Florida Beaches

Sun 14/6

06:30-07:15

2 stops18h 45m

£727

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Thu 4/6

08:40-19:09

2 stops16h 29m

Panama City NW Florida Beaches

Sun 14/6

17:08-14:35

2 stops15h 27m

£752

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Sun 26/4

11:20-19:36

2 stops14h 16m

Panama City NW Florida Beaches

Sun 3/5

18:46-14:35

2 stops13h 49m

£766
Cheapest one-way

LondonPanama City

LHR - ECP

LHRECP

London Heathrow

Fri 19/6

10:00-13:51

1 stop33h 51m

£485

Flights are sorted by cheapest return flights first.

Deals found on 30/3

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

Best time to book a flight from Heathrow to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Heathrow with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from London Heathrow Airport to Panama City

How far ahead should I book a flight from London Heathrow Airport to Panama City, Florida?

Use this chart to determine the optimal time to book a return flight from Heathrow to Panama City. Price data was last updated on 2 April 2026.

Booking 34 days in advance of your planned departure date is, on average, the best time to get cheap flights from London Heathrow Airport to Panama City, Florida. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from London Heathrow Airport to Panama City, Florida?

Currently, June is the cheapest month in which you can book a flight from London Heathrow Airport to Panama City, Florida (average of £336). Flying from London Heathrow Airport to Panama City, Florida in December is currently the most expensive (average of £495). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from London Heathrow Airport to Panama City, Florida?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 2 April 2026.
Read reviews from past customers who have flown with KLM,Virgin Atlantic, andUnited Airlines from London Heathrow Airport to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,485 reviews
Check prices

Crew

8.4

Entertainment

7.1

Overall

7.7

Comfort

7.6

Boarding

7.8

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7.7
Good
1,485 reviews
KLM
7.7
Good
1,485 reviews
Check prices

Crew

8.4

Entertainment

7.1

Overall

7.7

Comfort

7.6

Boarding

7.8

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Virgin Atlantic
7.5
Good
685 reviews
KLM
7.7
Good
1,485 reviews
Check prices

Crew

8.4

Entertainment

7.1

Overall

7.7

Comfort

7.6

Boarding

7.8

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
United Airlines
7.4
Good
9,536 reviews
KLM
7.7
Good
1,485 reviews
Check prices

Crew

8.4

Entertainment

7.1

Overall

7.7

Comfort

7.6

Boarding

7.8

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from Heathrow to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from London Heathrow?

    Most people fly into Panama City NW Florida Beaches (ECP) if they book a flight to Panama City from London Heathrow. On average, NW Florida Beaches has 0 inbound flights from London Heathrow per day from 3 airlines. Panama City NW Florida Beaches is conveniently located just 16.0 mi from Panama City’s city center.

  • How long is the flight from London Heathrow Airport to Panama City, Florida?

    United Airlines and KLM can get you from London Heathrow Airport to Panama City, Florida in just under 12h 06m. Your travel time can differ by up to 21h 45m. The distance from London Heathrow Airport to Panama City, Florida is about 4416 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What are the cheapest airlines flying from London Heathrow Airport to Panama City, Florida round-trip?

    United Airlines, at £351, was found to be the cheapest airline from London Heathrow Airport to Panama City, Florida.Alternate airlines flying return to your destination include Virgin Atlantic and KLM. United Airlines is priced at 44% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Heathrow to Panama City that include hotel bookings?

    Yes. In addition to deals on Heathrow to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Heathrow to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Heathrow to Panama City.

  • Can I find deals for business class flights from Heathrow to Panama City?

    Yes. Cheapflights offers flight deals from Heathrow to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from London Heathrow Airport to Panama City, Florida?

    Currently, June is the cheapest month in which you can book a flight from London Heathrow Airport to Panama City, Florida (average of £336). Flying from London Heathrow Airport to Panama City, Florida in December is currently the most expensive (average of £495). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Heathrow to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Heathrow to Panama City

Discover the top 3 airlines that operate flights from Heathrow to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 2 April 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest£351Average£620FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
Virgin AtlanticCheapest£470Average£574FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£490Average£903FlexibilityNo cancel feeOn-time75%
Search KLM flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Heathrow to Panama City?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Heathrow to Panama City. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Heathrow to Panama City?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Panama City from Heathrow.

Can Cheapflights find flights from Heathrow to Panama City with no change fees?

Yes! Cheapflights helps users easily find flights from Heathrow to Panama City with no change fees.

Can Cheapflights notify me if prices for flights from Heathrow to Panama City become cheaper?

Of course! You can now track prices for flights from Heathrow to Panama City and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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