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Cheap flights from Frankfurt am Main Airport to Panama City from £476

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel.
FRA — PTY
23 Apr — 30 Apr1
1 adult

Cheap flight deals from Frankfurt to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Frankfurt (FRA) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 18 April 2025.

Round-trip from

£476

Popular in

December

Cheapest in

May

Average price

£537
United Airlines
  • United Airlines
  • 2/9-16/9
  • 4 total stops
  • 54h 15m total
  • Frankfurt am Main to Panama City
Search Deals
Highest demand for flights based on searches. 10% potential increase in price (£48 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease (£18 potential savings vs. average return price).
Search Deals
Average for round-trip flights in April 2025
Search Deals

Find flight deals from Frankfurt to Panama City

Cheapest flights from Frankfurt to Panama City
Explore the most affordable flight options available from Frankfurt to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 18 April 2025.

Tue 2/909:55FRA - PTY
2 stops34h 55mUnited Airlines
Tue 16/909:45PTY - FRA
2 stops19h 20mUnited Airlines
Deal found 17/4£476
Sun 15/607:05FRA - PTY
1 stop17h 40mMultiple Airlines
Mon 23/618:50PTY - FRA
1 stop17h 20mMultiple Airlines
Deal found 17/4£487
Thu 26/610:55FRA - PTY
1 stop14h 45mAir Europa
Mon 7/720:25PTY - FRA
1 stop14h 25mAir Europa
Deal found 17/4£503
Wed 11/610:15FRA - PTY
1 stop13h 35mKLM
Wed 18/618:50PTY - FRA
1 stop15h 25mKLM
Deal found 17/4£569
Tue 11/1114:55FRA - PTY
1 stop35h 05mTurkish Airlines
Sun 23/1118:55PTY - FRA
1 stop21h 20mTurkish Airlines
Deal found 17/4£623
Sun 9/1109:50FRA - PTY
1 stop34h 02mDelta
Tue 25/1115:17PTY - FRA
1 stop35h 23mDelta
Deal found 17/4£649
Mon 1/1210:30FRA - PTY
Nonstop12h 15mCondor
Thu 18/1218:45PTY - FRA
Nonstop11h 10mCondor
Deal found 17/4£686

Cheapflights Fare Finder

Customise your flight search to find flights from Frankfurt to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 18 April 2025.
Use the filters below to find and compare flights from Frankfurt am Main Airport to Panama City that are best for you.

Fly from

Frankfurt

Fly to

Panama City

Route

Depart

Return

Price

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Tue 2/9

09:55-13:50

2 stops34h 55m

Panama City Tocumen Intl

Tue 16/9

09:45-12:05

2 stops19h 20m

£476

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Sun 15/6

07:05-17:45

1 stop17h 40m

Panama City Tocumen Intl

Mon 23/6

18:50-19:10

1 stop17h 20m

£487

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Thu 26/6

10:55-18:40

1 stop14h 45m

Panama City Tocumen Intl

Mon 7/7

20:25-17:50

1 stop14h 25m

£503

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Wed 11/6

10:15-16:50

1 stop13h 35m

Panama City Tocumen Intl

Wed 18/6

18:50-17:15

1 stop15h 25m

£569

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Tue 14/10

11:00-12:47

2 stops56h 47m

Panama City Tocumen Intl

Fri 24/10

14:12-08:50

2 stops35h 38m

£649

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Thu 3/7

14:25-20:00

1 stop36h 35m

Panama City Tocumen Intl

Wed 23/7

20:00-17:30

1 stop38h 30m

£681

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Mon 30/6

20:00-21:10

2 stops32h 10m

Panama City Tocumen Intl

Wed 23/7

03:20-08:35

2 stops22h 15m

£1,278

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Wed 18/6

21:50-02:40

Nonstop11h 50m

£1,053

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Wed 18/6

10:55-18:40

1 stop14h 45m

£1,316

Flights are sorted by cheapest return flights first.

Deals found on 17/4

Best time to book a flight from Frankfurt to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Frankfurt with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Frankfurt am Main Airport to Panama City

How far ahead should I book a flight from Frankfurt am Main Airport to Panama City?

Use this chart to determine the optimal time to book a return flight from Frankfurt to Panama City. Price data was last updated on 11 April 2025.

To ensure you get the cheapest price possible for a flight from Frankfurt am Main Airport to Panama City, you should look to book at least 48 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Frankfurt am Main Airport to Panama City?

Currently, April is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Panama City (average of £763). Flying from Frankfurt am Main Airport to Panama City in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 10.0 - 340.0 inches per month. October is typically the wettest month, when rainfall can reach 340.0 mm. February is typically the driest time to visit Panama City when rainfall is around 10.0 mm.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 27.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 26.0 C).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 18 April 2025.
Delta
8.0
Very Good
7,917 reviews
Check prices

Entertainment

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Anonymous,Aug 2023

SAN - ATL

We got returned to the gate because of a disruptive passenger and didn’t take off until 45 minutes later than scheduled but landed only 15 minutes late. All handled well.
Delta
8.0
Very Good
7,917 reviews
Delta
8.0
Very Good
7,917 reviews
Check prices

Entertainment

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Anonymous,Aug 2023

SAN - ATL

We got returned to the gate because of a disruptive passenger and didn’t take off until 45 minutes later than scheduled but landed only 15 minutes late. All handled well.
KLM
7.8
Good
1,329 reviews
Delta
8.0
Very Good
7,917 reviews
Check prices

Entertainment

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Anonymous,Aug 2023

SAN - ATL

We got returned to the gate because of a disruptive passenger and didn’t take off until 45 minutes later than scheduled but landed only 15 minutes late. All handled well.
United Airlines
7.4
Good
8,667 reviews
Delta
8.0
Very Good
7,917 reviews
Check prices

Entertainment

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Anonymous,Aug 2023

SAN - ATL

We got returned to the gate because of a disruptive passenger and didn’t take off until 45 minutes later than scheduled but landed only 15 minutes late. All handled well.
Turkish Airlines
7.3
Good
3,769 reviews
Delta
8.0
Very Good
7,917 reviews
Check prices

Entertainment

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Anonymous,Aug 2023

SAN - ATL

We got returned to the gate because of a disruptive passenger and didn’t take off until 45 minutes later than scheduled but landed only 15 minutes late. All handled well.
Air Europa
6.9
Okay
509 reviews
Delta
8.0
Very Good
7,917 reviews
Check prices

Entertainment

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Anonymous,Aug 2023

SAN - ATL

We got returned to the gate because of a disruptive passenger and didn’t take off until 45 minutes later than scheduled but landed only 15 minutes late. All handled well.

Related info for your journey

Find useful and relevant information for your journey from Frankfurt to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Frankfurt am Main?

    For a flight from Frankfurt am Main to Panama City, you will be flying into Tocumen Intl. Panama City Tocumen Intl (PTY) is just 11.4 mi from the center of the city. Tocumen Intl is the only Panama City airport and it handles 0 inbound flights from Frankfurt am Main per day. 0 airlines have flights to Panama City Tocumen Intl from Frankfurt am Main on a regular basis.

  • What are the cheapest airlines flying from Frankfurt am Main Airport to Panama City round-trip?

    Our cheapest airline available from Frankfurt am Main Airport to Panama City is United Airlines. Our recent data shows that you can find tickets from as low as £476 on this airline. Additional options worth looking into are Air Europa and KLM, starting at £503 and £569 round-trip. United Airlines is 13% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Frankfurt to Panama City that include hotel bookings?

    Yes. In addition to deals on Frankfurt to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Frankfurt to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Frankfurt to Panama City.

  • Can I find deals for business class flights from Frankfurt to Panama City?

    Yes. Cheapflights offers flight deals from Frankfurt to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Frankfurt am Main Airport to Panama City?

    Currently, April is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Panama City (average of £763). Flying from Frankfurt am Main Airport to Panama City in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Frankfurt am Main Airport?

Book flights to Frankfurt am Main Airport if you plan to visit one of these locations
San Blas

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