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Cheap flights from Madrid, Spain to Panama City from £359

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — PTY
2 Apr — 9 Apr1
1 adult

Cheapflights Tip: The best prices from Madrid Barajas to Panama City Tocumen Intl are usually found in May or September, booked 44 days in advance, depart on a Tuesday or Friday and return on a Monday

Cheap flight deals from Madrid to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 28 March 2025.

Round-trip from

£484

One-way from

£359

Popular in

December

Cheapest in

May

Average price

£531
Air France
  • Air France
  • 20/5-1/6
  • 2 total stops
  • 31h 40m total
  • Madrid to Panama City
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Air Europa
  • Air Europa
  • 5/5
  • Nonstop
  • 10h 35m total
  • Madrid to Panama City
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Highest demand for flights based on searches. 9% potential increase in price (£47 potential increase over avg. return price).
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Cheapest flight prices on average. 3% potential price decrease (£16 potential savings vs. average return price).
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Average for round-trip flights in March 2025
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Find flight deals from Madrid to Panama City

Cheapest flights from Madrid to Panama City
Explore the most affordable flight options available from Madrid to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 28 March 2025.

Tue 20/506:00MAD - PTY
1 stop17h 50mMultiple Airlines
Sun 1/619:55PTY - MAD
1 stop13h 50mMultiple Airlines
Deal found 28/3£484
Mon 12/510:50MAD - PTY
1 stop15h 41mUnited Airlines
Mon 19/522:55PTY - MAD
2 stops24h 45mUnited Airlines
Deal found 28/3£494
Mon 20/1015:05MAD - PTY
Nonstop10h 35mAir Europa
Tue 11/1121:30PTY - MAD
Nonstop9h 35mAir Europa
Deal found 28/3£513
Sun 31/810:05MAD - PTY
1 stop33h 49mDelta
Fri 12/914:14PTY - MAD
1 stop36h 21mDelta
Deal found 28/3£550
Mon 5/520:25MAD - PTY
1 stop27h 25mKLM
Sun 25/518:50PTY - MAD
1 stop31h 45mKLM
Deal found 27/3£561
Thu 27/1110:00MAD - PTY
2 stops40h 01mAir France
Thu 4/1220:50PTY - MAD
1 stop14h 10mAir France
Deal found 28/3£584
Sat 28/612:00MAD - PTY
Nonstop10h 40mIberia
Mon 7/717:20PTY - MAD
Nonstop10h 05mIberia
Deal found 28/3£626
Sun 11/501:30MAD - PTY
1 stop15h 40mAvianca
Sun 1/603:20PTY - MAD
1 stop37h 10mAvianca
Deal found 27/3£770
Sat 28/618:20MAD - PTY
1 stop32h 40mTurkish Airlines
Sat 12/720:00PTY - MAD
1 stop34h 35mTurkish Airlines
Deal found 28/3£779

Cheapflights Fare Finder

Customise your flight search to find flights from Madrid to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 28 March 2025.
Use the filters below to find and compare flights from Madrid to Panama City that are best for you.

Fly from

Madrid

Fly to

Panama City

Route

Depart

Return

Price

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Tue 20/5

06:00-16:50

1 stop17h 50m

Panama City Tocumen Intl

Sun 1/6

19:55-16:45

1 stop13h 50m

£484

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Mon 12/5

10:50-19:31

1 stop15h 41m

Panama City Tocumen Intl

Mon 19/5

22:55-06:40

2 stops24h 45m

£494

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Tue 20/5

15:05-18:40

Nonstop10h 35m

Panama City Tocumen Intl

Sun 1/6

20:25-13:15

Nonstop9h 50m

£535

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Sun 31/8

10:05-12:54

1 stop33h 49m

Panama City Tocumen Intl

Fri 12/9

14:14-09:35

1 stop36h 21m

£550

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Mon 5/5

20:25-16:50

1 stop27h 25m

Panama City Tocumen Intl

Sun 25/5

18:50-09:35

1 stop31h 45m

£561

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Sat 28/6

12:00-15:40

Nonstop10h 40m

Panama City Tocumen Intl

Mon 7/7

17:20-10:25

Nonstop10h 05m

£626

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Sat 28/6

06:00-17:45

1 stop18h 45m

Panama City Tocumen Intl

Mon 7/7

19:55-16:45

1 stop13h 50m

£769

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Sun 11/5

01:30-10:10

1 stop15h 40m

Panama City Tocumen Intl

Sun 1/6

03:20-23:30

1 stop37h 10m

£770

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Sat 28/6

07:40-18:20

2 stops41h 40m

Panama City Tocumen Intl

Sat 12/7

20:00-16:50

1 stop37h 50m

£779

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Thu 28/8

22:05-16:15

2 stops49h 10m

Panama City Tocumen Intl

Fri 12/9

22:50-13:30

2 stops55h 40m

£2,852

Flights are sorted by cheapest return flights first.

Deals found on 28/3

Showing 1-10 of 16 results
1
2

Best time to book a flight from Madrid to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Madrid with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Panama City

How far ahead should I book a flight from Madrid to Panama City?

Use this chart to determine the optimal time to book a return flight from Madrid to Panama City. Price data was last updated on 21 March 2025.

The best time to book flights from Madrid to Panama City is 44 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Madrid to Panama City?

Currently, April is the cheapest month in which you can book a flight from Madrid to Panama City (average of £763). Flying from Madrid to Panama City in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to PTY?

Find hourly flight availability from Madrid to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 28 March 2025.

When flying from Madrid to Panama City, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 6% versus a flight at midday.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 10.0 - 340.0 inches per month. October is typically the wettest month, when rainfall can reach 340.0 mm. February is typically the driest time to visit Panama City when rainfall is around 10.0 mm.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 27.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 26.0 C).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 28 March 2025.
Read reviews from past customers who have flown Emirates, Delta and KLM from Madrid to Panama City. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Emirates
8.0
Very Good
3,190 reviews
Check prices

Crew

8.3

Comfort

8.0

Overall

8.0

Entertainment

8.2

Boarding

8.1

Food

7.8

Reviews

1 / 20
2.0
Mediocre

Umair,Jul 2024

LHE - DXB

Worst experience. The staff at the airport were unprofessional, uncourtious, disrespectful and straight up discriminating. I will never travel via emirates again. And the flight was delayed too.
Emirates
8.0
Very Good
3,190 reviews
Emirates
8.0
Very Good
3,190 reviews
Check prices

Crew

8.3

Comfort

8.0

Overall

8.0

Entertainment

8.2

Boarding

8.1

Food

7.8

Reviews

1 / 20
2.0
Mediocre

Umair,Jul 2024

LHE - DXB

Worst experience. The staff at the airport were unprofessional, uncourtious, disrespectful and straight up discriminating. I will never travel via emirates again. And the flight was delayed too.
Delta
8.0
Very Good
7,897 reviews
Emirates
8.0
Very Good
3,190 reviews
Check prices

Crew

8.3

Comfort

8.0

Overall

8.0

Entertainment

8.2

Boarding

8.1

Food

7.8

Reviews

1 / 20
2.0
Mediocre

Umair,Jul 2024

LHE - DXB

Worst experience. The staff at the airport were unprofessional, uncourtious, disrespectful and straight up discriminating. I will never travel via emirates again. And the flight was delayed too.
KLM
7.8
Good
1,321 reviews
Emirates
8.0
Very Good
3,190 reviews
Check prices

Crew

8.3

Comfort

8.0

Overall

8.0

Entertainment

8.2

Boarding

8.1

Food

7.8

Reviews

1 / 20
2.0
Mediocre

Umair,Jul 2024

LHE - DXB

Worst experience. The staff at the airport were unprofessional, uncourtious, disrespectful and straight up discriminating. I will never travel via emirates again. And the flight was delayed too.
Air France
7.4
Good
1,424 reviews
Emirates
8.0
Very Good
3,190 reviews
Check prices

Crew

8.3

Comfort

8.0

Overall

8.0

Entertainment

8.2

Boarding

8.1

Food

7.8

Reviews

1 / 20
2.0
Mediocre

Umair,Jul 2024

LHE - DXB

Worst experience. The staff at the airport were unprofessional, uncourtious, disrespectful and straight up discriminating. I will never travel via emirates again. And the flight was delayed too.
United Airlines
7.4
Good
8,603 reviews
Emirates
8.0
Very Good
3,190 reviews
Check prices

Crew

8.3

Comfort

8.0

Overall

8.0

Entertainment

8.2

Boarding

8.1

Food

7.8

Reviews

1 / 20
2.0
Mediocre

Umair,Jul 2024

LHE - DXB

Worst experience. The staff at the airport were unprofessional, uncourtious, disrespectful and straight up discriminating. I will never travel via emirates again. And the flight was delayed too.

Related info for your journey

Find useful and relevant information for your journey from Madrid to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Madrid to Panama City?

    You will need to book a flight from Madrid Barajas to Panama City Tocumen Intl if you want to fly from Madrid to Panama City. At least 2 different airlines have flights from Barajas (MAD) to Tocumen Intl (PTY) on a regular basis. There are 2 flights to Panama City from the Madrid airport per day. If you manage to book one that is nonstop, then you can expect the flight time from MAD to PTY to be around 10h 35m.

  • How popular is this Madrid to Panama City flight route?

    Flights from Madrid Barajas to Panama City Tocumen Intl have been viewed 15 times in the past calendar month.

  • What are the cheapest airlines flying from Madrid to Panama City round-trip?

    Our cheapest airline available from Madrid to Panama City is United Airlines. Our recent data shows that you can find tickets from as low as £494 on this airline. Additional options worth looking into are Air Europa and Delta, starting at £535 and £550 round-trip. United Airlines is 19% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Madrid to Panama City one-way?

    For one-way options, check prices for Air Europa. According to our data, you can fly for as low as £359. Users have also found prices from £387 and £445 on Avianca and Iberia, respectively.

  • What are the most reliable airlines from Madrid to Panama City?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Madrid to Panama City on time: Qatar Airways (72%), Iberia (72%), EL AL (72%).

  • Can I find deals for flights from Madrid to Panama City that include hotel bookings?

    Yes. In addition to deals on Madrid to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Panama City.

  • Can I find deals for business class flights from Madrid to Panama City?

    Yes. Cheapflights offers flight deals from Madrid to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Panama City?

    Currently, April is the cheapest month in which you can book a flight from Madrid to Panama City (average of £763). Flying from Madrid to Panama City in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
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Top 2 airlines flying from Madrid to Panama City

Discover the top 2 airlines that operate flights from Madrid to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 28 March 2025.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapest£453Average£615FlexibilityNo cancel feeOn-time83%
Search Air Europa flights
IberiaCheapest£576Average£735FlexibilityNo cancel feeOn-time77%
Search Iberia flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Madrid to Panama City?

Deals for Madrid to Panama City flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Madrid to Panama City?

Cheapflights helps you find that perfect flight to Panama City from Madrid by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Madrid to Panama City with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Madrid to Panama City, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Madrid to Panama City become cheaper?

Not ready to book yet? You can track prices for flights from Madrid to Panama City on Cheapflights with our Price Alert feature and get notified when better prices are available.

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