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Cheap flights from Madrid, Spain to Panama City from £451

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 27/5. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — PTY
26 Feb — 5 Mar1
1 adult

The best prices from Madrid Barajas to Panama City Tocumen Intl are usually found in May or September, booked 44 days in advance, depart on a Tuesday or Friday and return on a Monday

Cheap flight deals from Madrid to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 21 February 2025.

Round-trip from

£451

Popular in

December

Cheapest in

May

Average price

£547

Good round-trip deal

£556 or less
KLM
  • KLM
  • 27/5-11/6
  • 2 total stops
  • 52h 15m total
  • Madrid to Panama City
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Highest demand for flights based on searches. 9% potential increase in price (£50 potential increase over avg. return price).
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Cheapest flight prices on average. 3% potential price decrease (£17 potential savings vs. average return price).
Search Deals
Average for round-trip flights in February 2025
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Price to beat on a round-trip flight from Madrid Barajas to Panama City Tocumen Intl.
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Find flight deals from Madrid to Panama City

Cheapest flights from Madrid to Panama City
Explore the most affordable flight options available from Madrid to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 21 February 2025.

Tue 27/517:10MAD - PTY
1 stop30h 40mKLM
Wed 11/618:50PTY - MAD
1 stop21h 35mKLM
Deal found 21/2£451
Sun 25/515:05MAD - PTY
Nonstop10h 35mAir Europa
Wed 11/620:25PTY - MAD
Nonstop9h 50mAir Europa
Deal found 20/2£509
Fri 28/211:00MAD - PTY
1 stop33h 02mDelta
Sat 29/314:20PTY - MAD
1 stop36h 15mDelta
Deal found 20/2£547
Mon 7/412:00MAD - PTY
Nonstop11h 05mIberia
Sat 12/417:35PTY - MAD
Nonstop9h 50mIberia
Deal found 20/2£584
Sat 22/323:55MAD - PTY
1 stop15h 45mMultiple Airlines
Thu 10/417:35PTY - MAD
Nonstop9h 50mMultiple Airlines
Deal found 20/2£589
Tue 25/212:25MAD - PTY
2 stops61h 20mAir France
Wed 21/518:50PTY - MAD
2 stops33h 30mAir France
Deal found 20/2£711
Sun 23/216:20MAD - PTY
1 stop14h 00mAvianca
Sun 2/318:30PTY - MAD
1 stop12h 55mAvianca
Deal found 20/2£764
Tue 25/212:00MAD - PTY
2 stops36h 20mTurkish Airlines
Wed 21/521:55PTY - MAD
1 stop32h 45mTurkish Airlines
Deal found 20/2£775

Find flights from Madrid to Panama City within your budget

Customise your flight search to find flights from Madrid to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 February 2025.

Fly from

Madrid

Fly to

Panama City

Route

Depart

Return

Price

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Tue 27/5

17:10-16:50

1 stop30h 40m

Panama City Tocumen Intl

Wed 11/6

18:50-23:25

1 stop21h 35m

£451

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Sun 25/5

15:05-18:40

Nonstop10h 35m

Panama City Tocumen Intl

Wed 11/6

20:25-13:15

Nonstop9h 50m

£509

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Tue 18/3

09:00-12:55

2 stops33h 55m

Panama City Tocumen Intl

Sat 29/3

14:20-08:35

1 stop36h 15m

£547

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Mon 7/4

12:00-16:05

Nonstop11h 05m

Panama City Tocumen Intl

Sat 12/4

17:35-10:25

Nonstop9h 50m

£584

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Sat 22/3

23:55-09:40

1 stop15h 45m

Panama City Tocumen Intl

Thu 10/4

17:35-10:25

Nonstop9h 50m

£589

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Wed 21/5

10:05-16:50

2 stops37h 45m

Panama City Tocumen Intl

Wed 4/6

14:02-09:35

1 stop36h 33m

£698

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Thu 13/3

00:35-09:40

1 stop15h 05m

Panama City Tocumen Intl

Sat 29/3

21:55-23:30

1 stop18h 35m

£764

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Mon 17/3

17:50-18:20

2 stops30h 30m

Panama City Tocumen Intl

Fri 28/3

19:50-09:25

1 stop31h 35m

£774

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Thu 29/5

12:45-13:50

2 stops32h 05m

Panama City Tocumen Intl

Wed 11/6

09:45-16:45

2 stops24h 00m

£954

MadridPanama City

MAD - PTY

MADPTY

Madrid Barajas

Mon 10/3

03:15-16:11

1 stop18h 56m

£471

Flights are sorted by cheapest return flights first.

Deals found on 20/2

Showing 1-10 of 13 results
1
2

Best time to book a flight from Madrid to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Madrid with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Madrid to Panama City

Get recent, data-driven insights about flights from Madrid to Panama City including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Madrid to Panama City?

Use this chart to determine the optimal time to book a return flight from Madrid to Panama City. Price data was last updated on 14 February 2025.

The best time to book flights from Madrid to Panama City is 44 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Madrid to Panama City?

Currently, April is the cheapest month in which you can book a flight from Madrid to Panama City (average of £763). Flying from Madrid to Panama City in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to PTY?

Find hourly flight availability from Madrid to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 21 February 2025.

When flying from Madrid to Panama City, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 6% versus a flight at midday.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 10.0 - 340.0 inches per month. October is typically the wettest month, when rainfall can reach 340.0 mm. February is typically the driest time to visit Panama City when rainfall is around 10.0 mm.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 27.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 26.0 C).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 21 February 2025.
Read reviews from past customers who have flown Delta, KLM and Air France from Madrid to Panama City. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very Good
8,212 reviews
Check prices

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

4.0
Okay

Peter,Oct 2023

MSP - GEG

The amount of carry on is put of control. We were in group 3 boarding and there was no room in upper storage for our 1 bag (between 2 people) Just because we can’t afford to up grade our seats… $2000 more. We get penaltized. Make us feel less than

Delta
8.0
Very Good
8,212 reviews
Delta
8.0
Very Good
8,212 reviews
Check prices

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

4.0
Okay

Peter,Oct 2023

MSP - GEG

The amount of carry on is put of control. We were in group 3 boarding and there was no room in upper storage for our 1 bag (between 2 people) Just because we can’t afford to up grade our seats… $2000 more. We get penaltized. Make us feel less than

KLM
7.8
Good
1,333 reviews
Delta
8.0
Very Good
8,212 reviews
Check prices

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

4.0
Okay

Peter,Oct 2023

MSP - GEG

The amount of carry on is put of control. We were in group 3 boarding and there was no room in upper storage for our 1 bag (between 2 people) Just because we can’t afford to up grade our seats… $2000 more. We get penaltized. Make us feel less than

Air France
7.4
Good
1,449 reviews
Delta
8.0
Very Good
8,212 reviews
Check prices

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

4.0
Okay

Peter,Oct 2023

MSP - GEG

The amount of carry on is put of control. We were in group 3 boarding and there was no room in upper storage for our 1 bag (between 2 people) Just because we can’t afford to up grade our seats… $2000 more. We get penaltized. Make us feel less than

United Airlines
7.4
Good
8,759 reviews
Delta
8.0
Very Good
8,212 reviews
Check prices

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

4.0
Okay

Peter,Oct 2023

MSP - GEG

The amount of carry on is put of control. We were in group 3 boarding and there was no room in upper storage for our 1 bag (between 2 people) Just because we can’t afford to up grade our seats… $2000 more. We get penaltized. Make us feel less than

Turkish Airlines
7.3
Good
3,832 reviews
Delta
8.0
Very Good
8,212 reviews
Check prices

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

4.0
Okay

Peter,Oct 2023

MSP - GEG

The amount of carry on is put of control. We were in group 3 boarding and there was no room in upper storage for our 1 bag (between 2 people) Just because we can’t afford to up grade our seats… $2000 more. We get penaltized. Make us feel less than

Related info for your journey

Find useful and relevant information for your journey from Madrid to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Madrid to Panama City?

    You will need to book a flight from Madrid Barajas to Panama City Tocumen Intl if you want to fly from Madrid to Panama City. At least 2 different airlines have flights from Barajas (MAD) to Tocumen Intl (PTY) on a regular basis. There are 4 flights to Panama City from the Madrid airport per day. If you manage to book one that is nonstop, then you can expect the flight time from MAD to PTY to be around 10h 35m.

  • How popular is this Madrid to Panama City flight route?

    Flights from Madrid Barajas to Panama City Tocumen Intl have been viewed 15 times in the past calendar month.

  • What are the cheapest airlines flying from Madrid to Panama City round-trip?

    Our cheapest airline available from Madrid to Panama City is KLM. Our recent data shows that you can find tickets from as low as £451 on this airline. Additional options worth looking into are Air Europa and Delta, starting at £509 and £547 round-trip. KLM is 28% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Madrid to Panama City one-way?

    For one-way options, check prices for Air France. According to our data, you can fly for as low as £474. Users have also found prices from £564 and £2,099 on Turkish Airlines and Air Europa, respectively.

  • What are the most reliable airlines from Madrid to Panama City?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Madrid to Panama City on time: China Eastern (85%), Qatar Airways (71%), Iberia (71%).

  • What are the cheapest flights from Madrid to Panama City?

    The cheapest flight price from Madrid to Panama City is £464. On average you can expect to pay £600. The most popular route, (Madrid Barajas - Panama City Tocumen Intl), can usually be booked for £600.

  • Can I find deals for flights from Madrid to Panama City that include hotel bookings?

    Yes. In addition to deals on Madrid to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Panama City.

  • Can I find deals for business class flights from Madrid to Panama City?

    Yes. Cheapflights offers flight deals from Madrid to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Panama City?

    Currently, April is the cheapest month in which you can book a flight from Madrid to Panama City (average of £763). Flying from Madrid to Panama City in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
San Blas

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Top 2 airlines flying from Madrid to Panama City

Discover the top 2 airlines that operate flights from Madrid to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 February 2025.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapest£464Average£631FlexibilityNo cancel feeOn-time83%
Search Air Europa flights
IberiaCheapest£590Average£721FlexibilityNo cancel feeOn-time77%
Search Iberia flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Madrid to Panama City?

Deals for Madrid to Panama City flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Madrid to Panama City?

Cheapflights helps you find that perfect flight to Panama City from Madrid by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Madrid to Panama City with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Madrid to Panama City, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Madrid to Panama City become cheaper?

Not ready to book yet? You can track prices for flights from Madrid to Panama City on Cheapflights with our Price Alert feature and get notified when better prices are available.

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