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Cheap flights from Mexico City to Panama City from £175

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 22/3. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — PTY
26 Feb — 5 Mar1
1 adult

The best prices from Mexico City Benito Juarez to Panama City Tocumen Intl are usually found in February or March, booked 54 days in advance, depart on a Tuesday or Monday and return on a Wednesday

Cheap flight deals from Mexico City to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 21 February 2025.

Round-trip from

£384

One-way from

£175

Popular in

July

Cheapest in

February

Average price

£343

Good one-way deal

£306 or less
Copa Airlines
  • Copa Airlines
  • 11/4-27/4
  • Nonstop
  • 7h 38m total
  • Mexico City to Panama City
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Avianca
  • Avianca
  • 22/3
  • 1 total stop
  • 14h 50m total
  • Mexico City to Panama City
Search Deals
Highest demand for flights based on searches. 9% potential increase in price (£32 potential increase over avg. return price).
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Cheapest flight prices on average. 1% potential price decrease (£4 potential savings vs. average return price).
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Average for round-trip flights in February 2025
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Price to beat on a one-way flight from Mexico City Benito Juarez to Panama City Tocumen Intl.
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Find flight deals from Mexico City to Panama City

Cheapest flights from Mexico City to Panama City
Explore the most affordable flight options available from Mexico City to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 21 February 2025.

Fri 14/1100:40MEX - PTY
1 stop38h 50mAvianca
Sat 22/1120:05PTY - MEX
1 stop16h 15mAvianca
Deal found 20/2£364
Fri 11/402:00MEX - PTY
Nonstop3h 46mCopa Airlines
Sun 27/421:23PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 20/2£384
Thu 14/808:55MEX - PTY
Nonstop3h 52mAeromexico
Wed 20/815:02PTY - MEX
Nonstop3h 38mAeromexico
Deal found 20/2£404
Sun 6/404:40MEX - PTY
1 stop10h 32mUnited Airlines
Sun 13/410:00PTY - MEX
1 stop14h 10mUnited Airlines
Deal found 20/2£893

Find flights from Mexico City to Panama City within your budget

Customise your flight search to find flights from Mexico City to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 February 2025.

Fly from

Mexico City

Fly to

Panama City

Route

Depart

Return

Price

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Fri 11/4

02:00-06:46

Nonstop3h 46m

Panama City Tocumen Intl

Sun 27/4

21:23-00:15

Nonstop3h 52m

£384

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Thu 14/8

08:55-13:47

Nonstop3h 52m

Panama City Tocumen Intl

Wed 20/8

15:02-17:40

Nonstop3h 38m

£404

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Sat 5/4

00:40-16:30

1 stop14h 50m

Panama City Tocumen Intl

Sun 13/4

11:05-23:00

1 stop12h 55m

£408

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Sun 6/4

04:40-16:12

1 stop10h 32m

Panama City Tocumen Intl

Sun 13/4

10:00-23:10

1 stop14h 10m

£893

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Sat 22/3

00:40-16:30

1 stop14h 50m

£175

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Sat 31/5

01:40-06:24

Nonstop3h 44m

£428

Flights are sorted by cheapest return flights first.

Deals found on 20/2

Best time to book a flight from Mexico City to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mexico City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Mexico City to Panama City

Get recent, data-driven insights about flights from Mexico City to Panama City including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Mexico City to Panama City?

Use this chart to determine the optimal time to book a return flight from Mexico City to Panama City. Price data was last updated on 14 February 2025.

The best time to book flights from Mexico City to Panama City is 54 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Mexico City to Panama City?

Currently, April is the cheapest month in which you can book a flight from Mexico City to Panama City (average of £763). Flying from Mexico City to Panama City in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MEX to PTY?

Find hourly flight availability from Mexico City to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 21 February 2025.

One of the essential ways to save on airfare from Mexico City to Panama City is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 40% on airfare.

Weekly flight availability from Mexico City to Panama City

Explore weekly flight availability from Mexico City to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 21 February 2025.

The most flights from MEX to PTY are scheduled on a Wednesday (9 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 10.0 - 340.0 inches per month. October is typically the wettest month, when rainfall can reach 340.0 mm. February is typically the driest time to visit Panama City when rainfall is around 10.0 mm.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 27.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 26.0 C).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 21 February 2025.
Read through reviews of airlines operating flights from Mexico City to Panama City, such as Copa Airlines, Aeromexico and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,510 reviews
Check prices

Crew

8.1

Overall

7.6

Boarding

7.8

Entertainment

6.9

Food

6.9

Comfort

7.4

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Copa Airlines
7.6
Good
1,510 reviews
Copa Airlines
7.6
Good
1,510 reviews
Check prices

Crew

8.1

Overall

7.6

Boarding

7.8

Entertainment

6.9

Food

6.9

Comfort

7.4

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Aeromexico
7.5
Good
1,771 reviews
Copa Airlines
7.6
Good
1,510 reviews
Check prices

Crew

8.1

Overall

7.6

Boarding

7.8

Entertainment

6.9

Food

6.9

Comfort

7.4

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

United Airlines
7.4
Good
8,759 reviews
Copa Airlines
7.6
Good
1,510 reviews
Check prices

Crew

8.1

Overall

7.6

Boarding

7.8

Entertainment

6.9

Food

6.9

Comfort

7.4

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Avianca
6.8
Okay
2,435 reviews
Copa Airlines
7.6
Good
1,510 reviews
Check prices

Crew

8.1

Overall

7.6

Boarding

7.8

Entertainment

6.9

Food

6.9

Comfort

7.4

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Mexico City to Panama City?

    If you book a flight from Mexico City to Panama City, you will be flying from Benito Juarez to Tocumen Intl. Flights to Panama City Tocumen Intl (PTY) from Mexico City Benito Juarez (MEX) take 3h 40m for a nonstop flight. There are 6 flights from Benito Juarez to Panama City per day from 1 airline.

  • How popular is this Mexico City to Panama City flight route?

    The Mexico City Benito Juarez to Panama City Tocumen Intl flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Mexico City to Panama City round-trip?

    Currently priced at £384, Copa Airlines will fly you from Mexico City to Panama City and back. In addition to Copa Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Aeromexico and Avianca - these airlines can fly you to your destination from £404 and £408, respectively.

  • What are the cheapest flights from Mexico City to Panama City?

    Looking for the cheapest flight from Mexico City to Panama City? While on average our users pay £346, our data indicates the cheapest price to be £146. The most popular route (Mexico City Benito Juarez - Panama City Tocumen Intl), is priced around £454.

  • Can I find deals for flights from Mexico City to Panama City that include hotel bookings?

    Yes. In addition to deals on Mexico City to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Panama City.

  • Can I find deals for business class flights from Mexico City to Panama City?

    Yes. Cheapflights offers flight deals from Mexico City to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Panama City?

    Currently, April is the cheapest month in which you can book a flight from Mexico City to Panama City (average of £763). Flying from Mexico City to Panama City in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Mexico City?

Book flights to Mexico City if you plan to visit one of these locations
San Blas

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Top airline flying from Mexico City to Panama City

Discover the top airline that operate flights from Mexico City to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 February 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest£332Average£468FlexibilityNo cancel feeOn-time70%
Search Copa Airlines flights

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Why should you use Cheapflights to find cheap flight tickets from Mexico City to Panama City?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Panama City from Mexico City.

Can Cheapflights find flights from Mexico City to Panama City with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Mexico City to Panama City flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Mexico City to Panama City become cheaper?

Yes! Start tracking prices for Mexico City to Panama City flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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