To ensure you get the cheapest price possible for a flight from Cancún to Santiago de Querétaro, you should look to book at least 86 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Cancún to Santiago de Querétaro as you normally would.
The most flights from CUN to QRO are scheduled on a Tuesday (4 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (3 on average).
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