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Cheap flights from Madrid, Spain to Santiago from £314

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/5. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
4 May — 11 May1
1 adult

Cheapflights Tip: The best prices from Madrid Barajas to Santiago Arturo Merino Benitez are usually found in March or April, booked 79 days in advance, depart on a Wednesday or Tuesday and return on a Monday

Cheap flight deals from Madrid to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 29 April 2025.

Round-trip from

£662

One-way from

£314

Popular in

December

Cheapest in

March

Average price

£702
Delta
  • Delta
  • 1/9-30/9
  • 3 total stops
  • 64h 40m total
  • Madrid to Santiago
Iberia
  • Iberia
  • 15/5
  • Nonstop
  • 13h 25m total
  • Madrid to Santiago
Highest demand for flights based on searches. 5% potential increase in price (£36 potential increase over avg. return price).
Cheapest flight prices on average. 2% potential price decrease (£16 potential savings vs. average return price).
Average for round-trip flights in April 2025

Find flight deals from Madrid to Santiago

Cheapest flights from Madrid to Santiago
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 29 April 2025.

Tue 4/1111:00MAD - SCL
1 stop24h 00mDelta
Sun 16/1123:15SCL - MAD
2 stops36h 10mDelta
Deal found 29/4£654
Wed 10/1213:20MAD - SCL
2 stops26h 50mAir Canada
Sun 18/108:35SCL - MAD
1 stop19h 25mAir Canada
Deal found 29/4£659
Mon 5/520:25MAD - SCL
2 stops41h 45mMultiple Airlines
Wed 11/610:00SCL - MAD
1 stop17h 10mMultiple Airlines
Deal found 28/4£664
Fri 6/607:10MAD - SCL
2 stops23h 35mLATAM Airlines
Sun 15/620:25SCL - MAD
2 stops33h 35mLATAM Airlines
Deal found 27/4£703
Wed 21/501:30MAD - SCL
1 stop17h 55mAvianca
Thu 5/614:30SCL - MAD
1 stop17h 35mAvianca
Deal found 28/4£713
Sun 23/1111:05MAD - SCL
2 stops49h 45mUnited Airlines
Fri 6/322:45SCL - MAD
2 stops41h 20mUnited Airlines
Deal found 28/4£750
Mon 10/1112:55MAD - SCL
Nonstop13h 20mIberia
Mon 24/1123:55SCL - MAD
Nonstop12h 40mIberia
Deal found 28/4£784
Fri 16/517:10MAD - SCL
2 stops21h 15mKLM
Thu 12/609:55SCL - MAD
2 stops41h 40mKLM
Deal found 28/4£787
Wed 10/1210:00MAD - SCL
1 stop27h 05mAmerican Airlines
Tue 20/121:30SCL - MAD
1 stop28h 35mAmerican Airlines
Deal found 29/4£817
Thu 20/1111:55MAD - SCL
2 stops25h 50mTurkish Airlines
Thu 5/311:40SCL - MAD
2 stops42h 45mTurkish Airlines
Deal found 28/4£820

Cheapflights Fare Finder

Customise your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 29 April 2025.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.

Fly from

Madrid

Fly to

Santiago

Route

Depart

Return

Price

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Mon 1/9

10:05-07:00

1 stop26h 55m

Santiago Arturo Merino Benitez

Tue 30/9

21:40-16:25

2 stops37h 45m

£662

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Fri 6/6

07:10-00:45

2 stops23h 35m

Santiago Arturo Merino Benitez

Sun 15/6

20:25-12:00

2 stops33h 35m

£703

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Wed 21/5

01:30-13:25

1 stop17h 55m

Santiago Arturo Merino Benitez

Thu 5/6

14:30-14:05

1 stop17h 35m

£713

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Mon 2/6

17:30-07:35

1 stop20h 05m

Santiago Arturo Merino Benitez

Mon 9/6

10:55-05:35

Nonstop12h 40m

£715

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sat 13/9

23:59-08:24

Nonstop13h 25m

Santiago Arturo Merino Benitez

Sat 11/10

11:55-05:35

Nonstop12h 40m

£784

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Fri 16/5

17:10-08:25

2 stops21h 15m

Santiago Arturo Merino Benitez

Thu 12/6

09:55-09:35

2 stops41h 40m

£787

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Thu 15/5

23:59-07:24

Nonstop13h 25m

£314

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Thu 29/5

06:10-02:35

2 stops26h 25m

£409

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sun 1/6

13:10-04:15

1 stop21h 05m

£415

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sat 16/8

10:05-07:00

1 stop26h 55m

£541

Flights are sorted by cheapest return flights first.

Deals found on 28/4

Showing 1-10 of 13 results
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Best time to book a flight from Madrid to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santiago

How far ahead should I book a flight from Madrid to Santiago?

Use this chart to determine the optimal time to book a return flight from Madrid to Santiago. Price data was last updated on 25 April 2025.

The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 79 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Madrid to Santiago?

Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago (average of £1,031). Flying from Madrid to Santiago in December is currently the most expensive (average of £1,468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to SCL?

Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 29 April 2025.

A simple way to save on the total cost of your ticket is to fly from Madrid to Santiago at midday. If you’re flexible enough to do this you can expect to save up to 5% on your trip compared to booking a flight in the morning.

Weekly flight availability from Madrid to Santiago

Explore weekly flight availability from Madrid to Santiago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 29 April 2025.

The most flights from MAD to SCL are scheduled on a Tuesday (17 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (10 on average).

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 70.0 inches per month. June is typically the wettest month, when rainfall can reach 70.0 mm. January is typically the driest time to visit Santiago when rainfall is around 0.0 mm.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 21.0 C. Travellers hoping to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 8.0 C).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 29 April 2025.
Read reviews from past customers who have flown Delta, KLM and LATAM Airlines from Madrid to Santiago. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
8.0
Very Good

Comfort

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Comfort

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Comfort

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Comfort

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Comfort

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airports do I use to fly from Madrid to Santiago?

    To fly from Madrid to Santiago, you need to book a flight from Barajas (MAD) to Arturo Merino Benitez (SCL). Nonstop flights to Santiago Arturo Merino Benitez from Madrid Barajas take 13h 15m on average. When it comes time to book airfare, you have a few options: there are 13 outbound flights from Barajas to Arturo Merino Benitez offered by 3 different airlines.

  • How popular is this Madrid to Santiago flight route?

  • What are the cheapest airlines flying from Madrid to Santiago round-trip?

    Cheapflights users have booked flights from Madrid to Santiago round-trip from £662. Other airlines that can offer you cheap pricing are LATAM Airlines, from £703, and Avianca, from £713. Users have found that Delta is 14% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Madrid to Santiago one-way?

    To fly one-way, consider booking your trip with Iberia, which is currently one of the cheapest options available, starting at £314. Avianca flights start at £415 while deals on Delta start at £541 one-way.

  • What are the most reliable airlines from Madrid to Santiago?

    No one likes to see their flight delayed. When booking a flight from Madrid to Santiago consider choosing Finnair (88%), Cathay Pacific (85%) or LATAM Airlines (82%) as they are the most reliable in getting you off to your destination on time.

  • Can I find deals for flights from Madrid to Santiago that include hotel bookings?

    Yes. In addition to deals on Madrid to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santiago.

  • Can I find deals for business class flights from Madrid to Santiago?

    Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Santiago?

    Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago (average of £1,031). Flying from Madrid to Santiago in December is currently the most expensive (average of £1,468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

Complete your trip to Santiago by adding a car hire and/or hotel booking to your travel itinerary.

Top 3 airlines flying from Madrid to Santiago

Discover the top 3 airlines that operate flights from Madrid to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 29 April 2025.
AirlineCheapestAverageFlexibilityOn-time
IberiaCheapest£456Average£666FlexibilityNo cancel feeOn-time77%
Search Iberia flights
British AirwaysCheapest£518Average£552FlexibilityNo cancel feeOn-time70%
Search British Airways flights
LATAM AirlinesCheapest£635Average£809FlexibilityNo cancel feeOn-time81%
Search LATAM Airlines flights

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How does Cheapflights help users find flights from Madrid to Santiago?

Cheapflights makes it easy to find Madrid to Santiago flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Madrid to Santiago?

Millions of users choose and trust Cheapflights to book the best flight deals from Madrid to Santiago for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Madrid to Santiago with no change fees?

Certainly. Search results for flights to Santiago from Madrid shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Madrid to Santiago become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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