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Cheap flights from Madrid, Spain to Santiago from £308

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 27/4. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
2 Apr — 9 Apr1
1 adult

Cheapflights Tip: The best prices from Madrid Barajas to Santiago Arturo Merino Benitez are usually found in May or March, booked 86 days in advance, depart on a Wednesday or Tuesday and return on a Monday

Cheap flight deals from Madrid to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 28 March 2025.

Round-trip from

£629

One-way from

£308

Popular in

December

Cheapest in

May

Average price

£648
Delta
  • Delta
  • 16/5-24/5
  • 4 total stops
  • 101h 30m total
  • Madrid to Santiago
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Iberia
  • Iberia
  • 27/4
  • Nonstop
  • 13h 15m total
  • Madrid to Santiago
Search Deals
Highest demand for flights based on searches. 7% potential increase in price (£50 potential increase over avg. return price).
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Cheapest flight prices on average. 3% potential price decrease (£18 potential savings vs. average return price).
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Average for round-trip flights in March 2025
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Find flight deals from Madrid to Santiago

Cheapest flights from Madrid to Santiago
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 28 March 2025.

Fri 28/310:00MAD - SCL
1 stop24h 20mDelta
Wed 7/520:40SCL - MAD
2 stops36h 55mDelta
Deal found 27/3£602
Wed 29/1011:40MAD - SCL
1 stop29h 20mBritish Airways
Tue 25/1113:05SCL - MAD
1 stop19h 35mBritish Airways
Deal found 27/3£608
Fri 24/1013:20MAD - SCL
Nonstop13h 15mMultiple Airlines
Tue 18/1113:05SCL - MAD
1 stop19h 35mMultiple Airlines
Deal found 27/3£697
Sun 9/1111:05MAD - SCL
2 stops49h 45mUnited Airlines
Mon 17/1122:45SCL - MAD
2 stops29h 20mUnited Airlines
Deal found 27/3£704
Sun 18/513:10MAD - SCL
1 stop21h 05mAvianca
Tue 3/623:55SCL - MAD
1 stop17h 35mAvianca
Deal found 27/3£724
Tue 10/614:25MAD - SCL
1 stop16h 20mLATAM Airlines
Tue 24/616:10SCL - MAD
1 stop19h 10mLATAM Airlines
Deal found 27/3£767
Sun 12/1013:20MAD - SCL
Nonstop13h 15mIberia
Tue 28/1023:55SCL - MAD
Nonstop12h 40mIberia
Deal found 28/3£769
Sun 9/1117:50MAD - SCL
2 stops43h 55mTurkish Airlines
Thu 20/1111:40SCL - MAD
2 stops42h 45mTurkish Airlines
Deal found 27/3£804
Thu 4/1213:00MAD - SCL
1 stop22h 50mAmerican Airlines
Sun 1/221:30SCL - MAD
2 stops28h 15mAmerican Airlines
Deal found 27/3£807
Tue 10/612:45MAD - SCL
2 stops30h 40mAir Canada
Tue 24/623:55SCL - MAD
2 stops26h 25mAir Canada
Deal found 27/3£912
Mon 12/520:25MAD - SCL
2 stops41h 45mKLM
Fri 23/509:55SCL - MAD
2 stops41h 40mKLM
Deal found 27/3£938

Cheapflights Fare Finder

Customise your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 28 March 2025.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.

Fly from

Madrid

Fly to

Santiago

Route

Depart

Return

Price

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Fri 16/5

12:40-07:00

2 stops48h 20m

Santiago Arturo Merino Benitez

Sat 24/5

20:40-07:50

2 stops53h 10m

£629

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Tue 23/9

11:45-11:30

1 stop28h 45m

Santiago Arturo Merino Benitez

Tue 7/10

16:00-17:30

1 stop20h 30m

£679

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sun 18/5

13:10-04:15

1 stop21h 05m

Santiago Arturo Merino Benitez

Tue 3/6

23:55-23:30

1 stop17h 35m

£724

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Tue 10/6

14:25-00:45

1 stop16h 20m

Santiago Arturo Merino Benitez

Tue 24/6

16:10-17:20

1 stop19h 10m

£767

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Wed 3/9

23:59-07:24

Nonstop13h 25m

Santiago Arturo Merino Benitez

Sat 20/9

11:25-15:00

1 stop22h 35m

£819

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Tue 17/6

12:00-07:45

2 stops49h 45m

Santiago Arturo Merino Benitez

Thu 18/9

10:40-16:50

2 stops25h 10m

£907

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sun 18/5

17:15-12:00

2 stops24h 45m

Santiago Arturo Merino Benitez

Tue 3/6

10:35-12:00

1 stop19h 25m

£908

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Tue 10/6

12:45-13:25

2 stops30h 40m

Santiago Arturo Merino Benitez

Tue 24/6

23:55-08:20

2 stops26h 25m

£912

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Mon 12/5

20:25-08:10

2 stops41h 45m

Santiago Arturo Merino Benitez

Fri 23/5

09:55-09:35

2 stops41h 40m

£938

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sun 27/4

13:20-20:35

Nonstop13h 15m

£308

Flights are sorted by cheapest return flights first.

Deals found on 27/3

Showing 1-10 of 15 results
1
2

Best time to book a flight from Madrid to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santiago

How far ahead should I book a flight from Madrid to Santiago?

Use this chart to determine the optimal time to book a return flight from Madrid to Santiago. Price data was last updated on 21 March 2025.

The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 86 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Madrid to Santiago?

Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago (average of £1,031). Flying from Madrid to Santiago in December is currently the most expensive (average of £1,468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to SCL?

Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 28 March 2025.

A simple way to save on the total cost of your ticket is to fly from Madrid to Santiago at midday. If you’re flexible enough to do this you can expect to save up to 5% on your trip compared to booking a flight in the morning.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 70.0 inches per month. June is typically the wettest month, when rainfall can reach 70.0 mm. January is typically the driest time to visit Santiago when rainfall is around 0.0 mm.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 21.0 C. Travellers hoping to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 8.0 C).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 28 March 2025.
Read reviews from past customers who have flown Delta, KLM and LATAM Airlines from Madrid to Santiago. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very Good
7,897 reviews
Check prices

Comfort

8.0

Overall

8.0

Food

7.3

Boarding

8.2

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very Good
7,897 reviews
Delta
8.0
Very Good
7,897 reviews
Check prices

Comfort

8.0

Overall

8.0

Food

7.3

Boarding

8.2

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
KLM
7.8
Good
1,321 reviews
Delta
8.0
Very Good
7,897 reviews
Check prices

Comfort

8.0

Overall

8.0

Food

7.3

Boarding

8.2

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
LATAM Airlines
7.5
Good
1,750 reviews
Delta
8.0
Very Good
7,897 reviews
Check prices

Comfort

8.0

Overall

8.0

Food

7.3

Boarding

8.2

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Turkish Airlines
7.3
Good
3,744 reviews
Delta
8.0
Very Good
7,897 reviews
Check prices

Comfort

8.0

Overall

8.0

Food

7.3

Boarding

8.2

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Air Canada
7.0
Good
8,981 reviews
Delta
8.0
Very Good
7,897 reviews
Check prices

Comfort

8.0

Overall

8.0

Food

7.3

Boarding

8.2

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Madrid to Santiago?

    To fly from Madrid to Santiago, you need to book a flight from Barajas (MAD) to Arturo Merino Benitez (SCL). Nonstop flights to Santiago Arturo Merino Benitez from Madrid Barajas take 13h 15m on average. When it comes time to book airfare, you have a few options: there are 5 outbound flights from Barajas to Arturo Merino Benitez offered by 3 different airlines.

  • How popular is this Madrid to Santiago flight route?

    This flight path from Madrid Barajas to Santiago Arturo Merino Benitez was viewed by 14 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Madrid to Santiago round-trip?

    Cheapflights users have booked flights from Madrid to Santiago round-trip from £629. Other airlines that can offer you cheap pricing are British Airways, from £679, and Avianca, from £724. Users have found that Delta is 19% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Madrid to Santiago one-way?

    To fly one-way, consider booking your trip with Iberia, which is currently one of the cheapest options available, starting at £308. Avianca flights start at £406 while deals on Delta start at £531 one-way.

  • What are the most reliable airlines from Madrid to Santiago?

    No one likes to see their flight delayed. When booking a flight from Madrid to Santiago consider choosing Finnair (95%), EL AL (92%) or LATAM Airlines (90%) as they are the most reliable in getting you off to your destination on time.

  • Can I find deals for flights from Madrid to Santiago that include hotel bookings?

    Yes. In addition to deals on Madrid to Santiago flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santiago.

  • Can I find deals for business class flights from Madrid to Santiago?

    Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Santiago?

    Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago (average of £1,031). Flying from Madrid to Santiago in December is currently the most expensive (average of £1,468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Santiago by adding a car hire and/or hotel booking to your travel itinerary.
Santiago car hire
Santiago Arturo Merino Benitez Airport car hire
Punta Arenas car hire
Puerto Montt car hire
Balmaceda car hire
Lastarria car hire

Top 3 airlines flying from Madrid to Santiago

Discover the top 3 airlines that operate flights from Madrid to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 28 March 2025.
AirlineCheapestAverageFlexibilityOn-time
IberiaCheapest£471Average£688FlexibilityNo cancel feeOn-time77%
Search Iberia flights
British AirwaysCheapest£535Average£554FlexibilityNo cancel feeOn-time70%
Search British Airways flights
LATAM AirlinesCheapest£656Average£835FlexibilityNo cancel feeOn-time81%
Search LATAM Airlines flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Madrid to Santiago?

Cheapflights makes it easy to find Madrid to Santiago flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Madrid to Santiago?

Millions of users choose and trust Cheapflights to book the best flight deals from Madrid to Santiago for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Madrid to Santiago with no change fees?

Certainly. Search results for flights to Santiago from Madrid shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Madrid to Santiago become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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