Find flights
When to book
Airlines
FAQs

Cheap flights from Manchester to South Carolina from £220

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 29/3. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — CHS
26 Jan — 2 Feb1
1 adult

Cheap flight deals from Manchester to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 21 January 2025.

Round-trip from

£514

One-way from

£220
17/3-26/3
  • 17/3-26/3
  • 4 total stops
  • 58h 18m total
  • Manchester to South Carolina
Search Deals
29/3
  • 29/3
  • 2 total stops
  • 49h 05m total
  • Manchester to South Carolina
Search Deals

Find flight deals from Manchester to South Carolina

Cheapest flights from Manchester to South Carolina
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 21 January 2025.

Mon 17/319:15MAN - MYR
2 stops32h 19mMultiple Airlines
Wed 26/307:06MYR - MAN
2 stops25h 59mMultiple Airlines
Deal found 20/1£514
Tue 4/307:40MAN - CHS
2 stops21h 17mFinnair
Sun 9/320:22CHS - MAN
2 stops15h 58mFinnair
Deal found 21/1£560
Tue 18/209:45MAN - GSP
2 stops15h 25mFinnair
Tue 25/216:49GSP - MAN
2 stops18h 36mFinnair
Deal found 20/1£562
Tue 4/311:55MAN - CHS
3 stops26h 58mMultiple Airlines
Sun 9/314:15CHS - MAN
2 stops16h 30mMultiple Airlines
Deal found 21/1£621
Tue 18/212:00MAN - GSP
1 stop13h 25mVirgin Atlantic
Tue 25/217:22GSP - MAN
2 stops20h 18mVirgin Atlantic
Deal found 20/1£627
Mon 2/607:00MAN - MYR
2 stops15h 24mFinnair
Thu 12/607:16MYR - MAN
2 stops23h 19mFinnair
Deal found 20/1£647
Mon 17/313:40MAN - MYR
2 stops25h 07mDelta
Wed 26/311:32MYR - MAN
1 stop16h 03mDelta
Deal found 19/1£650
Tue 4/314:00MAN - CHS
1 stop12h 48mVirgin Atlantic
Sun 9/317:03CHS - MAN
1 stop9h 57mVirgin Atlantic
Deal found 21/1£664
Wed 30/409:20MAN - GSP
2 stops16h 02mBritish Airways
Sat 17/518:09GSP - MAN
2 stops16h 36mBritish Airways
Deal found 20/1£676
Mon 17/306:05MAN - GSP
2 stops18h 01mAmerican Airlines
Fri 28/314:36GSP - MAN
2 stops17h 19mAmerican Airlines
Deal found 21/1£679
Wed 12/312:00MAN - CHS
1 stop13h 10mDelta
Fri 21/312:55CHS - MAN
2 stops17h 25mDelta
Deal found 21/1£680
Wed 30/412:45MAN - GSP
1 stop27h 15mDelta
Sat 17/517:05GSP - MAN
1 stop10h 30mDelta
Deal found 20/1£682

Find flights from Manchester to South Carolina within your budget

Customise your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 January 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Mon 17/3

19:15-23:34

2 stops32h 19m

Myrtle Beach Intl

Wed 26/3

07:06-13:05

2 stops25h 59m

£514

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Tue 4/3

07:40-23:57

2 stops21h 17m

Charleston

Sun 9/3

20:22-16:20

2 stops15h 58m

£560

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Tue 18/2

09:45-20:10

2 stops15h 25m

Greenville

Tue 25/2

16:49-16:25

2 stops18h 36m

£562

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Tue 4/3

11:55-09:53

3 stops26h 58m

Charleston

Sun 9/3

14:15-10:45

2 stops16h 30m

£621

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Tue 18/2

12:00-20:25

1 stop13h 25m

Greenville

Tue 25/2

17:22-18:40

2 stops20h 18m

£627

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Mon 2/6

07:00-17:24

2 stops15h 24m

Myrtle Beach Intl

Thu 12/6

07:16-11:35

2 stops23h 19m

£647

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Mon 17/3

13:40-10:47

2 stops25h 07m

Myrtle Beach Intl

Wed 26/3

11:32-07:35

1 stop16h 03m

£650

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Tue 4/3

14:00-21:48

1 stop12h 48m

Charleston

Sun 9/3

17:03-07:00

1 stop9h 57m

£664

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Wed 30/4

09:20-20:22

2 stops16h 02m

Greenville

Sat 17/5

18:09-15:45

2 stops16h 36m

£676

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Mon 17/3

06:05-20:06

2 stops18h 01m

Greenville

Fri 28/3

14:36-11:55

2 stops17h 19m

£679

Flights are sorted by cheapest return flights first.

Deals found on 21/1

Showing 1-10 of 40 results
1
2
3
4

Best time to book a flight from Manchester to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Manchester to South Carolina

Get recent, data-driven insights about flights from Manchester to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Manchester to South Carolina?

Currently, April is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £731). Flying from Manchester to South Carolina in July is currently the most expensive (average of £970). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAN to SC?

Find hourly flight availability from Manchester to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 21 January 2025.

When flying from Manchester to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 61.0 - 183.0 inches per month. August is typically the wettest month, when rainfall can reach 183.0 mm. November is typically the driest time to visit South Carolina when rainfall is around 61.0 mm.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 28.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 9.0 C).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated 21 January 2025.
To help decide which airline to fly from Manchester to South Carolina, see what other customers have to say about American Airlines, British Airways and KLM. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very Good
8,521 reviews
Check prices

Food

7.3

Comfort

8.0

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very Good
8,521 reviews
Delta
8.0
Very Good
8,521 reviews
Check prices

Food

7.3

Comfort

8.0

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

KLM
7.8
Good
1,341 reviews
Delta
8.0
Very Good
8,521 reviews
Check prices

Food

7.3

Comfort

8.0

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Finnair
7.6
Good
1,286 reviews
Delta
8.0
Very Good
8,521 reviews
Check prices

Food

7.3

Comfort

8.0

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Virgin Atlantic
7.5
Good
665 reviews
Delta
8.0
Very Good
8,521 reviews
Check prices

Food

7.3

Comfort

8.0

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Air France
7.4
Good
1,490 reviews
Delta
8.0
Very Good
8,521 reviews
Check prices

Food

7.3

Comfort

8.0

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Manchester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to South Carolina?

    For a flight from Manchester to South Carolina, you will be flying from Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.

  • What are the cheapest airlines to fly from Manchester to South Carolina one-way?

    To fly one-way, consider booking your trip with TAP AIR PORTUGAL, which is currently one of the cheapest options available, starting at £724. Aer Lingus flights start at £795 while deals on Air France start at £797 one-way.

  • What are the most popular routes from Manchester to South Carolina?

    While some choose either Manchester - Charleston or Manchester - Greenville, Manchester - Charlotte Douglas is the most popular route from Manchester to South Carolina.

  • Can I find deals for flights from Manchester to South Carolina that include hotel bookings?

    Yes. In addition to deals on Manchester to South Carolina flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South Carolina.

  • Can I find deals for business class flights from Manchester to South Carolina?

    Yes. Cheapflights offers flight deals from Manchester to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to South Carolina?

    Currently, April is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £731). Flying from Manchester to South Carolina in July is currently the most expensive (average of £970). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Manchester to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Heathrow to John F Kennedy Intl flights
Heathrow to Newark flights
Gatwick to John F Kennedy Intl flights
Heathrow to LaGuardia flights
London City to John F Kennedy Intl flights
Gatwick to Newark flights
Heathrow to Miami flights
London City to Newark flights
Stansted to Stewart flights
Heathrow to Orlando flights
Heathrow to Los Angeles flights
Heathrow to Las Vegas flights
Manchester to John F Kennedy Intl flights
London City to Miami flights
Heathrow to O'Hare Intl flights
Luton to John F Kennedy Intl flights
Gatwick to Miami flights
Heathrow to Dulles Intl flights
Heathrow to San Francisco flights
Stansted to John F Kennedy Intl flights
Gatwick to LaGuardia flights
Heathrow to Boston flights
Heathrow to New Orleans flights
Heathrow to Baltimore flights
Heathrow to Dallas/Fort Worth flights
Manchester to Orlando flights
Gatwick to Orlando flights
Luton to Newark flights
Gatwick to Los Angeles flights
Heathrow to Seattle flights
Stansted to Newark flights
London City to Los Angeles flights
Heathrow to Hobby flights
Heathrow to Tampa flights
Heathrow to Atlanta flights
Heathrow to Nashville flights
London City to Orlando flights
Stansted to Miami flights
Manchester to Newark flights
Heathrow to Charlotte flights
Gatwick to Boston flights
Gatwick to Stewart flights
Heathrow to Denver flights
Heathrow to George Bush Intcntl flights
London City to Las Vegas flights
Heathrow to Ontario flights
Gatwick to San Francisco flights
Gatwick to O'Hare Intl flights
Manchester to LaGuardia flights
Heathrow to Baton Rouge flights

Top 6 airlines flying from Manchester to South Carolina

Discover the top 6 airlines that operate flights from Manchester to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 January 2025.
AirlineCheapestAverageFlexibilityOn-time
FinnairCheapest£477Average£766FlexibilityNo cancel feeOn-time76%
Search Finnair flights
British AirwaysCheapest£617Average£769FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£627Average£810FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£633Average£856FlexibilityNo cancel feeOn-time75%
Search KLM flights
Air FranceCheapest£648Average£911FlexibilityNo cancel feeOn-time77%
Search Air France flights
Aer LingusCheapest£774Average£955FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to South Carolina?

Deals for Manchester to South Carolina flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to South Carolina?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Manchester to South Carolina.

Can Cheapflights find flights from Manchester to South Carolina with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to South Carolina with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to South Carolina become cheaper?

Of course! You can now track prices for flights from Manchester to South Carolina and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.