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Cheap flights from Manchester to South Carolina from £550

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/8. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — CHS
22 Apr — 29 Apr1
1 adult

Cheap flight deals from Manchester to South Carolina

Keep the following information in mind while searching for Manchester to South Carolina flight deals. Data was last updated 17 April 2025.

Round-trip from

£659

One-way from

£550

Popular in

August

Cheapest in

February

Average price

£789
United Airlines
  • United Airlines
  • 3/6-17/6
  • 4 total stops
  • 58h 33m total
  • Manchester to South Carolina
Turkish Airlines
  • Turkish Airlines
  • 9/8
  • 2 total stops
  • 40h 00m total
  • Manchester to South Carolina
Highest demand for flights based on searches. 12% potential increase in price (£86 potential increase over avg. return price).
Cheapest flight prices on average. 3% potential price decrease (£23 potential savings vs. average return price).
Average for round-trip flights in April 2025

Find flight deals from Manchester to South Carolina

Cheapest flights from Manchester to South Carolina
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 April 2025.

Tue 3/605:55MAN - GSP
2 stops22h 51mUnited Airlines
Tue 17/617:18GSP - MAN
2 stops35h 42mUnited Airlines
Deal found 16/4£659
Wed 23/411:15MAN - SAV
2 stops17h 42mVirgin Atlantic
Wed 30/416:38SAV - MAN
1 stop10h 57mVirgin Atlantic
Deal found 16/4£661
Wed 23/414:15MAN - SAV
2 stops14h 42mDelta
Wed 30/411:14SAV - MAN
2 stops16h 06mDelta
Deal found 16/4£662
Fri 2/514:15MAN - CHS
1 stop28h 50mMultiple Airlines
Sat 31/509:43CHS - MAN
3 stops21h 52mMultiple Airlines
Deal found 16/4£665
Thu 8/514:15MAN - GSP
2 stops33h 59mVirgin Atlantic
Sun 18/519:59GSP - MAN
2 stops30h 46mVirgin Atlantic
Deal found 16/4£681
Wed 14/510:55MAN - CHS
2 stops15h 38mFinnair
Wed 11/618:24CHS - MAN
2 stops16h 11mFinnair
Deal found 16/4£705
Wed 14/510:55MAN - CHS
2 stops15h 38mBritish Airways
Wed 11/618:24CHS - MAN
2 stops16h 11mBritish Airways
Deal found 16/4£706
Tue 6/509:25MAN - CLT
2 stops15h 15mMultiple Airlines
Fri 9/511:52CLT - MAN
2 stops23h 58mMultiple Airlines
Deal found 15/4£706
Tue 20/513:05MAN - CHS
2 stops35h 43mIcelandair
Tue 17/611:30CHS - MAN
2 stops19h 10mIcelandair
Deal found 16/4£709
Wed 30/409:20MAN - GSP
2 stops16h 05mBritish Airways
Sat 17/518:28GSP - MAN
2 stops23h 12mBritish Airways
Deal found 16/4£710
Wed 14/511:55MAN - CHS
1 stop16h 49mVirgin Atlantic
Wed 11/607:00CHS - MAN
1 stop19h 45mVirgin Atlantic
Deal found 16/4£711
Wed 30/411:55MAN - GSP
1 stop14h 50mDelta
Sat 17/505:30GSP - MAN
1 stop22h 05mDelta
Deal found 16/4£716

Cheapflights Fare Finder

Customise your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 17 April 2025.
Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.

Fly from

Manchester

Fly to

South Carolina

Route

Depart

Return

Price

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Tue 3/6

05:55-23:46

2 stops22h 51m

Greenville

Tue 17/6

17:18-10:00

2 stops35h 42m

£659

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Fri 2/5

14:15-14:05

1 stop28h 50m

Charleston

Sat 31/5

09:43-12:35

3 stops21h 52m

£665

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Thu 8/5

12:35-20:15

1 stop12h 40m

Greenville

Sun 18/5

19:59-07:45

2 stops30h 46m

£681

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 14/5

10:55-21:33

2 stops15h 38m

Charleston

Wed 11/6

18:24-15:35

2 stops16h 11m

£705

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 14/5

10:55-21:33

2 stops15h 38m

Charleston

Wed 11/6

18:24-15:35

2 stops16h 11m

£706

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Tue 6/5

09:25-19:40

2 stops15h 15m

Charlotte Douglas

Fri 9/5

11:52-16:50

2 stops23h 58m

£706

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Tue 20/5

13:05-19:48

2 stops35h 43m

Charleston

Tue 17/6

11:30-11:40

2 stops19h 10m

£709

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Wed 30/4

09:20-20:25

2 stops16h 05m

Greenville

Sat 17/5

18:28-22:40

2 stops23h 12m

£710

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 14/5

11:55-23:44

1 stop16h 49m

Charleston

Wed 11/6

07:00-07:45

1 stop19h 45m

£711

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Wed 30/4

14:15-10:39

2 stops25h 24m

Greenville

Sat 17/5

05:30-08:35

1 stop22h 05m

£716

Flights are sorted by cheapest return flights first.

Deals found on 16/4

Showing 1-10 of 32 results
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Best time to book a flight from Manchester to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to South Carolina

What is the cheapest month to book a flight from Manchester to South Carolina?

Currently, April is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £731). Flying from Manchester to South Carolina in July is currently the most expensive (average of £970). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAN to SC?

Find hourly flight availability from Manchester to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 17 April 2025.

When flying from Manchester to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 61.0 - 183.0 inches per month. August is typically the wettest month, when rainfall can reach 183.0 mm. November is typically the driest time to visit South Carolina when rainfall is around 61.0 mm.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 28.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 9.0 C).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated 17 April 2025.
To help decide which airline to fly from Manchester to South Carolina, see what other customers have to say about Delta, Finnair and Air France. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
8.0
Very Good

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Manchester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Manchester to South Carolina?

    For a flight from Manchester to South Carolina, you will be flying from Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.

  • What are the most popular routes from Manchester to South Carolina?

  • Can I find deals for flights from Manchester to South Carolina that include hotel bookings?

    Yes. In addition to deals on Manchester to South Carolina flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South Carolina.

  • Can I find deals for business class flights from Manchester to South Carolina?

    Yes. Cheapflights offers flight deals from Manchester to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to South Carolina?

    Currently, April is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £731). Flying from Manchester to South Carolina in July is currently the most expensive (average of £970). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Manchester to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 8 airlines flying from Manchester to South Carolina

Discover the top 8 airlines that operate flights from Manchester to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 17 April 2025.
AirlineCheapestAverageFlexibilityOn-time
FinnairCheapest£532Average£712FlexibilityNo cancel feeOn-time76%
Search Finnair flights
Air FranceCheapest£559Average£845FlexibilityNo cancel feeOn-time77%
Search Air France flights
British AirwaysCheapest£568Average£720FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£573Average£751FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£576Average£804FlexibilityNo cancel feeOn-time75%
Search KLM flights
American AirlinesCheapest£601Average£735FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
DeltaCheapest£628Average£748FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
Aer LingusCheapest£793Average£939FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights

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How does Cheapflights help users find flights from Manchester to South Carolina?

Deals for Manchester to South Carolina flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to South Carolina?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Manchester to South Carolina.

Can Cheapflights find flights from Manchester to South Carolina with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to South Carolina with no change fees.

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Of course! You can now track prices for flights from Manchester to South Carolina and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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